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The primary antidote to brodifacoum poisoning is immediate administration of vitamin K 1 (dosage for humans: initially slow intravenous injections of 10–25 mg repeated at 3–6 hours until normalisation of the prothrombin time; then 10 mg orally four times daily as a "maintenance dose"). It is an extremely effective antidote, provided the ...
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The large 3-position substituent is required for anticoagulant activity. The primary mechanism of the 4-hydroxycoumarin drugs is the inhibition of vitamin K epoxide reductase . These compounds are not direct antagonists (in the pharmaceutical sense) of vitamin K, but rather act to deplete reduced vitamin K in tissues.
Other vitamin K deficient states include: biliary obstruction, intrahepatic cholestasis, intestinal malabsorption and chronic oral antibiotic administration. These are objectives of these poisons, as the sick animal normally stays in its nest, removing the need to clean up/dispose of dead animals.
A fter one full week in office, President Donald Trump sent a signal that his transformation of Washington was soon to take full force: The White House released an order Monday night to pause as ...
Coumarin dyes are extensively used as gain media in blue-green tunable organic dye lasers. [14] [15] [16] Among the various coumarin laser dyes are coumarins 480, 490, 504, 521, 504T, and 521T. [16]
iPlus TV [13] India's first official Islamic TV Satellite Channel registered with Ministry of Information & Broadcastingand with a valid uplinking/downlinking permission and approval and is being uplinked from Delhi to Insat 4A @83°E. iPlus TV relays high quality digital programs using latest high end technology. Interviews, talks, discussions ...
One of the four bodies handed over from Gaza to Israel on Thursday does not include a hostage, the Israel Defense Forces said, calling it a "very serious violation" by Hamas.