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Clomipramine, sold under the brand name Anafranil among others, is a tricyclic antidepressant (TCA). [5] It is used in the treatment of various conditions, most notably obsessive–compulsive disorder but also many other disorders, including hyperacusis, panic disorder, major depressive disorder, trichotillomania, [6] body dysmorphic disorder [7] [8] [9] and chronic pain. [5]
Clomipramine. Doxepin. Imipramine. Older antidepressant medications like tricyclic antidepressants typically have a higher risk of side effects than the more modern SSRI and SNRI medications ...
Side effects may also be less troublesome if treatment is initiated with low doses and then gradually increased, although this may also delay the beneficial effects. TCAs can behave like class 1A antiarrhythmics , as such, they can theoretically terminate ventricular fibrillation, decrease cardiac contractility and increase collateral blood ...
All-in-all, however, it is prescribed with caution to the elderly and with extreme caution to those with psychosis, as the general brain activity enhancement in combination with the "dementing" effects of anticholinergics increases the potential of imipramine to cause hallucinations, confusion and delirium in this population.
For adults older than 64, SSRI's seem to reduce the risk of both suicidal behavior. [116] In 2016 a study criticized the effects of the FDA Black Box suicide warning inclusion in the prescription. The authors discussed the suicide rates might increase also as a consequence of the warning. [132]
An elderly woman was viciously stabbed to death by her 88-year-old husband in front of her horrified family inside their Staten Island home Thursday night, according to police sources.
Seniors are generally at higher risk for complications and death from pneumonia due to weakened immune systems. However, risk factors vary from person to person. If you suspect your elderly loved ...
This article needs significant cleanup in relationship to the side effect issues of clomipramine. First of all, like many of the older tricyclics, this is a potent anticholinergic drug. It is grossly inadequate to suggest that "confusion" (an intrinsically vague term) is a caution.
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