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Serotonin's association with mood is most known for various forms of depression and bipolar disorders in humans. [198] Disorders caused by serotonergic activity potentially contribute to the many symptoms of major depression, such as overall mood, activity, suicidal thoughts and sexual and cognitive dysfunction .
Diurnal mood improvement was associated with activity of dorsal neural networks. Increased mean core temperature was also observed. One hypothesis proposed that depression was a result of a phase shift. [30] Daytime light exposure correlates with decreased serotonin transporter activity, which may underlie the seasonality of some depression. [31]
Bipolar disorder is a long-term mood disorder characterized by major fluctuations in mood — both high and low — that can impact daily functioning and behavior. ... like dopamine and serotonin ...
Mood disorders fall into seven groups, [2] including; abnormally elevated mood, such as mania or hypomania; depressed mood, of which the best-known and most researched is major depressive disorder (MDD) (alternatively known as clinical depression, unipolar depression, or major depression); and moods which cycle between mania and depression ...
Selective serotonin reuptake inhibitors, or SSRIs, are one of the most popular types of antidepressants today, and they’re often used to treat anxiety disorders. Serotonin is a neurotransmitter ...
To confirm major depressive disorder as the most likely diagnosis, other potential diagnoses must be considered, including dysthymia, adjustment disorder with depressed mood, or bipolar disorder. Dysthymia is a chronic, milder mood disturbance in which a person reports a low mood almost daily over a span of at least two years.
NHS figures show that the number of people in England taking antidepressants continues to rise, with 8.3m patients receiving them in 2021/22.
A serotonin pathway identifies aggregate projections from neurons which synthesize and communicate the monoamine neurotransmitter serotonin. [citation needed] These pathways are relevant to different psychiatric and neurological disorders. [1] [2] [3]
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