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There is a slight increase in dose proportionality in terms of peak and area-under-the-curve levels of THC with increasing oral doses over a range of 2.5 to 10 mg. [21] A high-fat meal delays time to peak concentrations of oral THC by 4 hours on average and increases area-under-the-curve exposure by 2.9-fold, but peak concentrations are not ...
Most cannabinoids are lipophilic (fat soluble) compounds that are easily stored in fat, thus yielding a long elimination half-life relative to other recreational drugs. The THC molecule, and related compounds, are usually detectable in drug tests from 3 days up to 10 days.
This is because they are fat-soluble, lipophilic molecules that accumulate in fatty tissues. [50] Research shows the effect of cannabinoids might be modulated by aromatic compounds produced by the cannabis plant, called terpenes. This interaction would lead to the entourage effect. [51]
Unlike alcohol, which is water soluble and evenly distributed through your blood, THC is fat soluble, which means it’s harder to test for in blood or breath. With edibles, THC concentrations in ...
Cannabis (/ ˈ k æ n ə b ɪ s /), [2] commonly known as marijuana (/ ˌ m æ r ə ˈ w ɑː n ə /), [3] weed, and pot, among other names, is a non-chemically uniform drug from the cannabis plant. Native to Central or South Asia, the cannabis plant has been used as a drug for both recreational and entheogenic purposes and in various ...
Most cannabinoids are lipophilic (fat soluble) compounds that easily store in fat, thus yielding a long elimination half-life relative to other recreational drugs. [1] Metabolites of cannabis are usually detectable in urine drug tests from 3 days up to 10 days according to Redwood Laboratories; heavy users can produce positive tests for 30 days ...
The alcohols extract undesirable water-soluble substances such as chlorophyll and sugars (which can be removed later by washing with water). Non-polar solvents such as benzene, chloroform and petroleum ether will not extract the water-soluble constituents of marijuana or hashish while still producing hash oil. In general, non-polar cannabis ...
11-Hydroxy-Δ 9-tetrahydrocannabinol (11-OH-Δ 9-THC, alternatively numbered as 7-OH-Δ 1-THC), usually referred to as 11-hydroxy-THC is the main active metabolite of tetrahydrocannabinol (THC), which is formed in the body after Δ 9-THC is consumed.