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THC and its 11-OH-THC and THC-COOH metabolites can be detected and quantified in blood, urine, hair, oral fluid or sweat using a combination of immunoassay and chromatographic techniques as part of a drug use testing program or in a forensic investigation. [57] [58] [59] There is ongoing research to create devices capable of detecting THC in ...
Laboratory evidence indicated that cannabidiol may reduce THC clearance, increasing plasma concentrations which may raise THC availability to receptors and enhance its effect in a dose-dependent manner. [59] [60] In vitro, cannabidiol inhibited the activity of voltage-dependent sodium and potassium channels, which may affect neural activity. [61]
Tetrahydrocannabinolic acid (THCA, 2-COOH-THC; conjugate base tetrahydrocannabinolate) is a precursor of tetrahydrocannabinol (THC), an active component of cannabis. [1]THCA is found in variable quantities in fresh, undried cannabis, but is progressively decarboxylated to THC with drying, and especially under intense heating such as when cannabis is smoked or cooked into cannabis edibles.
In the US, "industrial hemp" is classified by the federal government as cannabis containing no more than 0.3% THC by dry weight. This classification was established in the 2018 Farm Bill and was refined to include hemp-sourced extracts, cannabinoids, and derivatives in the definition of hemp.
The first private, stand-alone Care Quality Commission (CQC) registered cannabis clinic was opened by Sapphire medical in December 2019, [60] since then a number of private clinics have opened across the UK. The UK's first medical cannabis registry set up and run by Drug Science charity was launched in August 2020.
In 2016, the cannabis light Law 242/16 removed the need for authorization to plant certified cannabis seeds with levels of THC below 0.2%, which is lower than the 0.3% limit defined by the EU Regulation 2021/2115 of 2 December 2021, [24] while the detection of THC levels between 0.2% and 0.6% during field inspections is still considered ...
A survey in 2017 found that 27% of Israelis between the ages of 18 and 65 had consumed cannabis in the last year, up from 8.8% in 2009, [7] the highest rates of annual cannabis usage in the world, followed by Iceland and the US at 18% and 16% respectively.
A medical cannabis crop in Australia. Cannabis is a plant used in Australia for recreational, medicinal and industrial purposes. In 2022–23, 41% of Australians over the age of fourteen years had used cannabis in their lifetime and 11.5% had used cannabis in the last 12 months.