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3,3′,5,5′-Tetramethylbenzidine or TMB is a chromogenic substrate used in staining procedures in immunohistochemistry as well as being a visualising reagent used in enzyme-linked immunosorbent assays (). [1]
Benzidine (trivial name), also called 1,1'-biphenyl-4,4'-diamine (systematic name), is an organic compound with the formula (C 6 H 4 NH 2) 2. It is an aromatic amine. It is a component of a test for cyanide. Related derivatives are used in the production of dyes. Benzidine has been linked to bladder and pancreatic cancer. [2]
3,3′-Diaminobenzidine (DAB) is an organic compound with the formula (C 6 H 3 (NH 2) 2) 2.This derivative of benzidine is a precursor to polybenzimidazole, which forms fibers that are renowned for their chemical and thermal stability. [1]
Most people who take a drug test take a presumptive test, cheaper and faster than other methods of testing. However, it is less accurate and can render false results. The FDA recommends for confirmatory testing to be conducted and the placing of a warning label on the presumptive drug test: "This assay provides only a preliminary result.
The value q s is the sample's test statistic. (The notation | x | means the absolute value of x; the magnitude of x with the sign set to +, regardless of the original sign of x.) This q s test statistic can then be compared to a q value for the chosen significance level α from a table of the studentized range distribution.
Taber’s reagent is a diazo-phosphonate used for the one carbon homologation of an aldehyde to the alkyne which is next in the homologous series. Taber’s reagent allows this reaction to occur under ambient conditions, at a large scale, and at a lower cost relative to similar reagents.
This type of test is considered a diffusion test. [18] In agar and broth dilution methods, bacteria are placed in multiple small tubes with different concentrations of antibiotics. [14] Whether a bacterium is sensitive or not is determined by visual inspection or automatic optical methods, after a period of incubation. [5]
The test was first developed and described by the German physician Felix Mendel in 1908. [2] It is named after Charles Mantoux, a French physician who built on the work of Koch and Clemens von Pirquet to create his test in 1907. However, the test was unreliable due to impurities in tuberculin which tended to cause false results. [3]