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Leukocoria (also white pupillary reflex) is an abnormal white reflection from the retina of the eye. Leukocoria resembles eyeshine , but leukocoria can also occur in animals that lack eyeshine because their retina lacks a tapetum lucidum .
A relative afferent pupillary defect (RAPD), also known as a Marcus Gunn pupil (after Robert Marcus Gunn), is a medical sign observed during the swinging-flashlight test [1] whereupon the patient's pupils excessively dilate when a bright light is swung from the unaffected eye to the affected eye. The affected eye still senses the light and ...
The most common and obvious sign of retinoblastoma is an abnormal appearance of the retina as viewed through the pupil, the medical term for which is leukocoria, also known as amaurotic cat's eye reflex. [5] Other signs and symptoms include deterioration of vision, a red and irritated eye with glaucoma, and
Symptoms typically begin as blurred vision, usually pronounced when one eye is closed (due to the unilateral nature of the disease). Often the unaffected eye will compensate for the loss of vision in the other eye; however, this results in some loss of depth perception and parallax. Deterioration of sight may begin in either the central or ...
Although the pupillary response, in which the pupil dilates or constricts due to light is not usually called a "reflex", it is still usually considered a part of this topic. Adjustment to close-range vision is known as "the near response", while relaxation of the ciliary muscle to view distant objects is known as the "far response".
A complete physical examination is done to identify if a child has any associated systemic symptoms which may aid in a diagnosis of childhood cataracts. [4] In addition, a complete eye examination is done. [2] [4] This eye exam includes fixation, pupillary reflex test, and test for visual acuity. [4]
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However, if the eyes are asymmetrically affected, i.e. one eye's optic nerve is more damaged than the other, it will produce an important sign called an afferent pupillary defect. [citation needed] Defective light perception in one eye causes an asymmetrical pupillary constriction reflex called the afferent pupillary defect (APD). [citation needed]