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HER2 is so named because it has a similar structure to human epidermal growth factor receptor, or HER1. Neu is so named because it was derived from a rodent glioblastoma cell line, a type of neural tumor. ErbB-2 was named for its similarity to ErbB (avian erythroblastosis oncogene B), the oncogene later found to code for EGFR.
The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). In many cancer types, mutations affecting EGFR expression or activity could result in cancer. [6]
The timeline of discovery of Solar System planets and their natural satellites charts the progress of the discovery of new bodies over history. Each object is listed in chronological order of its discovery (multiple dates occur when the moments of imaging, observation, and publication differ), identified through its various designations (including temporary and permanent schemes), and the ...
This list of exoplanets discovered in 2024 is a list of confirmed exoplanets that were first reported in 2024. For exoplanets detected only by radial velocity , the listed value for mass is a lower limit.
The theory was initially proposed by Fred Hoyle in 1946, [1] who later refined it in 1954. [2] Further advances were made, especially to nucleosynthesis by neutron capture of the elements heavier than iron , by Margaret and Geoffrey Burbidge , William Alfred Fowler and Fred Hoyle in their famous 1957 B 2 FH paper , [ 3 ] which became one of the ...
c. 150 BCE – According to Strabo (1.1.9), Seleucus of Seleucia is the first to state that the tides are due to the attraction of the Moon, and that the height of the tides depends on the Moon's position relative to the Sun. [30] c. 150 BCE – Hipparchus uses parallax to determine that the distance to the Moon is roughly 380,000 km (236,100 ...
The International Designator, also known as COSPAR ID, is an international identifier assigned to artificial objects in space. [1] It consists of the launch year, a three-digit incrementing launch number of that year [n 1] and up to a three-letter code representing the sequential identifier of a piece in a launch.
Launch of Mariner 1 in 1962. The Mariner program was conducted by the American space agency NASA to explore other planets.Between 1962 and late 1973, NASA's Jet Propulsion Laboratory (JPL) designed and built 10 robotic interplanetary probes named Mariner to explore the inner Solar System – visiting the planets Venus, Mars and Mercury for the first time, and returning to Venus and Mars for ...