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Meningococcal meningitis is a form of bacterial meningitis. Meningitis is a disease caused by inflammation and irritation of the meninges, the membranes surrounding the brain and spinal cord. In meningococcal meningitis this is caused by the bacteria invading the cerebrospinal fluid and circulating through the central nervous system. Sub ...
When caused by Neisseria meningitidis, WFS is considered the most severe form of meningococcal sepsis. The onset of the illness is nonspecific with fever, rigors, vomiting, and headache. Soon a rash appears; first macular, not much different from the rose spots of typhoid, and rapidly becoming petechial and purpuric with a dusky
Charlotte Cleverley-Bisman developed severe meningococcal meningitis as a young child; in her case, the petechial rash progressed to gangrene and required amputation of all limbs. She survived the disease and became a poster child for a meningitis vaccination campaign in New Zealand.
"In severe cases, it may cause seizures, coma or a purple rash." Infants may show different signs such as poor feeding, irritability, bulging of the soft spot on their head or lethargy. Noted ...
They measure 3–10 mm, [3] whereas petechiae measure less than 3 mm, and ecchymoses greater than 1 cm. [4] Purpura is common with typhus and can be present with meningitis caused by meningococci or septicaemia. In particular, meningococcus (Neisseria meningitidis), a Gram-negative diplococcus organism, releases endotoxin when it lyses.
A meningococcal polysaccharide vaccine (MPSV4) has been available since the 1970s and is the only meningococcal vaccine licensed for people older than 55. MPSV4 may be used in people 2–55 years old if the MCV4 vaccines are not available or contraindicated. Two meningococcal conjugate vaccines (MCV4) are licensed for use in the U.S. The first ...
A non-blanching rash (NBR) is a skin rash that does not fade when pressed with, and viewed through, a glass. It is a characteristic of both purpuric and petechial rashes. [ 1 ] Individual purpura measure 3–10 mm (0.3–1 cm, 3 ⁄ 32 - 3 ⁄ 8 in), whereas petechiae measure less than 3 mm. [ 2 ]
Patients with measles will have the rash but there are other syndromes and infections that will display the same symptom such as patients with Kawasaki disease, [4] meningococcal petechiae or Waterhouse-Friderichsen syndrome, [4] Dengue, Roseola, congenital syphilis, [5] rubella, [4] Echovirus 9, [4] drug hypersensitivity reactions (in ...