Search results
Results from the WOW.Com Content Network
A primary imine in which C is attached to both a hydrocarbyl and a H (derived from an aldehyde) is called a primary aldimine; a secondary imine with such groups is called a secondary aldimine. [10] A primary imine in which C is attached to two hydrocarbyls (derived from a ketone) is called a primary ketimine ; a secondary imine with such groups ...
Ketimine Mannich catalysis has been identified as a synthetic tool for primary alcohols. [2] A useful path to dihydroquinazolinone, a precursor to drugs with anti-viral and cardiovascular benefits, was also found by Liu [22] et Al. using N-Heterocyclic carbene-catalyzation [4+2] annulation of β-methyl enals.
Addition of a Grignard reagent to a tert-butanesulfinyl aldimine or ketimine results in asymmetric addition to give the branched sulfinamide. The observed stereoselectivity can be rationalized by a six-membered ring transition structure, wherein both oxygen and nitrogen of the sulfinyl imine coordinate magnesium.
The ketimine is then subjected to the Bucherer-Bergs reagents, resulting in a 5,5'- disubstituted hydantoin 3. This reaction has three points of chemical diversity as the structure of the aziridine starting compound, the organometallic reagent, and the electrophile can all be varied to synthesize a different hydantoin.
General structure of a ketenimine. Ketenimines are a group of organic compounds sharing a common functional group with the general structure R 1 R 2 C=C=NR 3.A ketenimine is a cumulated alkene and imine and is related to an allene and a ketene.
Schiff bases have been investigated in relation to a wide range of contexts, including antimicrobial, antiviral and anticancer activity. They have also been considered for the inhibition of amyloid-β aggregation.
Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!
The lysine residue reforms the internal aldimine by kicking off α-iminobutyric acid. Afterwards the external ketimine is hydrolyzed, causing the formation of α-ketobutyrate. [7] The amino group on cystathionine is deprotonated and undergoes a nucleophilic attack of the internal aldimine.