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  2. Mycophenolic acid - Wikipedia

    en.wikipedia.org/wiki/Mycophenolic_acid

    Mycophenolate mofetil, a prodrug form of mycophenolic acid used in medicine. Mycophenolate mofetil is the morpholino‌ ethyl ester of mycophenolic acid; the ester masks the carboxyl group. [42] Mycophenolate mofetil is reported to have a pKa values of 5.6 for the morpholino moiety and 8.5 for the phenolic group.

  3. Tolcapone - Wikipedia

    en.wikipedia.org/wiki/Tolcapone

    Tolcapone is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa or levodopa/benserazide medications. Levodopa is a prodrug for dopamine, which reduces Parkinson symptoms; carbidopa and benserazide are aromatic L-amino acid decarboxylase (AADC) inhibitors.

  4. Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Parkinson's_disease

    Parkinson's disease (PD), or simply Parkinson's, is a neurodegenerative disease primarily of the central nervous system, affecting both motor and non-motor systems. Symptoms typically develop gradually, with non-motor issues becoming more prevalent as the disease progresses.

  5. Management of Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Management_of_Parkinson's...

    In the management of Parkinson's disease, due to the chronic nature of Parkinson's disease (PD), a broad-based program is needed that includes patient and family education, support-group services, general wellness maintenance, exercise, and nutrition. At present, no cure for the disease is known, but medications or surgery can provide relief ...

  6. Opicapone - Wikipedia

    en.wikipedia.org/wiki/Opicapone

    Opicapone, sold under the brand name Ongentys, is a medication which is administered together with levodopa in people with Parkinson's disease. [3] [6] [4] [5] Opicapone is a catechol-O-methyltransferase (COMT) inhibitor.

  7. List of long term side effects of antipsychotics - Wikipedia

    en.wikipedia.org/wiki/List_of_long_term_side...

    This article needs more reliable medical references for verification or relies too heavily on primary sources, specifically: Unsourced list of side effects, needs references. Please review the contents of the article and add the appropriate references if you can. Unsourced or poorly sourced material may be challenged and removed

  8. Entacapone - Wikipedia

    en.wikipedia.org/wiki/Entacapone

    Entacapone is used in addition to levodopa and carbidopa for people with Parkinson's disease to treat the signs and symptoms of end-of-dose "wearing-off." [5] "Wearing-off" is characterized by the re-appearance of both motor and non-motor symptoms of Parkinson's disease occurring towards the end of a previous levodopa and carbidopa dose. [6]

  9. Pharmacology of selegiline - Wikipedia

    en.wikipedia.org/wiki/Pharmacology_of_selegiline

    [22] [134] [135] [31] Loss of striatal dopamine reaches a level of 40% in healthy people by the age of 75, whereas in people with Parkinson's disease, the loss is around 70% at diagnosis and more than 90% at death. [22] Only about 0.1% of the human population develops Parkinson's disease.

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