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  2. Lifileucel - Wikipedia

    en.wikipedia.org/wiki/Lifileucel

    Lifileucel is the first tumor-derived T cell immunotherapy approved by the US Food and Drug Administration (FDA). [3] It was approved for medical use in the United States in February 2024. [ 2 ] [ 4 ]

  3. Activated PI3K delta syndrome - Wikipedia

    en.wikipedia.org/wiki/Activated_PI3K_Delta_Syndrome

    PI3kinase. The pathophysiology of activated PI3K delta syndrome has several aspects. [2] The normal function has P110δ (PI3K) involved in immune system regulation. [9]P110δ effect is not limited to the immune system; P110δ has a presence in transformed epithelial cells and cell adhesion molecules (airway inflammation), and research has been done on the possibility of P110δ in the nervous ...

  4. Cutaneous T-cell lymphoma - Wikipedia

    en.wikipedia.org/wiki/Cutaneous_T-cell_lymphoma

    Of all cancers involving lymphocytes, 2% of cases are cutaneous T cell lymphomas. [13] CTCL is more common in men and in African-American people. [10] The incidence of CTCL in men is 1.6 times higher than in women. [10] There is some evidence of a relationship with human T-lymphotropic virus (HTLV) with the adult T-cell leukemia/lymphoma ...

  5. FDA approves cure for sickle cell disease, the first ... - AOL

    www.aol.com/news/fda-approves-cure-sickle-cell...

    The FDA on Friday also approved a second treatment for sickle cell disease, called Lyfgenia, a gene therapy from drugmaker Bluebird Bio. Both treatments work by genetically modifying a patient’s ...

  6. Sézary disease - Wikipedia

    en.wikipedia.org/wiki/Sézary_disease

    Sézary disease, or Sézary syndrome, [1] is a type of cutaneous T-cell lymphoma that was first described by Albert Sézary. [2] The affected T cells, known as Sézary's cells or Lutzner cells, have pathological quantities of mucopolysaccharides. Sézary disease is sometimes considered a late stage of mycosis fungoides with lymphadenopathy. [3] [4]

  7. Primary immunodeficiency - Wikipedia

    en.wikipedia.org/wiki/Primary_immunodeficiency

    Primary immunodeficiencies are disorders in which part of the body's immune system is missing or does not function normally. [1] To be considered a primary immunodeficiency (PID), the immune deficiency must be inborn, not caused by secondary factors such as other disease, drug treatment, or environmental exposure to toxins.

  8. Dave Coulier of ‘Full House’ reveals cancer diagnosis - AOL

    www.aol.com/dave-coulier-full-house-reveals...

    (It) is a cancer that starts in cells called lymphocytes, which are part of the body’s immune system,” according to the American Cancer Society. “B-cell lymphomas make up most (about 85%) of ...

  9. Mesoblast shares tank after US FDA rejects cell therapy for ...

    www.aol.com/news/fda-rejects-mesoblasts-cell...

    The U.S. Food and Drug Administration (FDA) required more data to support marketing approval for the company's lead product remestemcel-L, Mesoblast said in a statement on Thursday. Mesoblast ...

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