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Management of tuberculosis refers to techniques and procedures utilized for treating tuberculosis (TB), or simply a treatment plan for TB. The medical standard for active TB is a short course treatment involving a combination of isoniazid , rifampicin (also known as Rifampin), pyrazinamide , and ethambutol for the first two months.
Peritoneal tuberculosis: Peritoneal tuberculosis most often presents as abdominal pain and ascites. It can occur most commonly following re-activation of a latent focus of tuberculosis. [3] Intestinal tuberculosis: Tuberculosis of the intestine can affect multiple areas of the bowel simultaneously. The bacilli penetrate the mucosa, cause ...
This severe form of TB disease, most common in young children and those with HIV, is called miliary tuberculosis. [97] People with this disseminated TB have a high fatality rate even with treatment (about 30%). [53] [98] In many people, the infection waxes and wanes. Tissue destruction and necrosis are often balanced by healing and fibrosis. [94]
Ethionamide is an antibiotic used to treat tuberculosis. [2] Specifically it is used, along with other antituberculosis medications, to treat active multidrug-resistant tuberculosis. [2] It is no longer recommended for leprosy. [3] [2] It is taken by mouth. [2] Ethionamide has a high rate of side effects. [4]
Rifampicin is used for the treatment of tuberculosis in combination with other antibiotics, such as pyrazinamide, isoniazid, and ethambutol. [10] For the treatment of tuberculosis, it is administered daily for at least six months. [11] Combination therapy is used to prevent the development of resistance and to shorten the length of treatment. [12]
Pyrazinamide is a medication used to treat tuberculosis. [2] For active tuberculosis, it is often used with rifampicin, isoniazid, and either streptomycin or ethambutol. [3] It is not generally recommended for the treatment of latent tuberculosis. [2] It is taken by mouth. [1]
(S,S)-(+)-Ethambutol is powerful and selective antitubercular drug.It is a typical example of an old drug that was introduced for clinical use in its unichiral form. . Ethambutol contains two constitutionally symmetrical chiral centers in its structure and exists in three stereoisomeric forms, the enantiomeric pair (+)-(S,S)- and (−)-(R,R)-ethambutol, along with the achiral stereoisomer called m
Asymptomatic elevation of serum liver enzyme concentrations occurs in 10% to 20% of people taking INH, and liver enzyme concentrations usually return to normal even when treatment is continued. [27] Isoniazid has a boxed warning for severe and sometimes fatal hepatitis, which is age-dependent at a rate of 0.3% in people 21 to 35 years old and ...
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