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Raynaud syndrome, also known as Raynaud's phenomenon, is a medical condition in which the spasm of small arteries causes episodes of reduced blood flow to end arterioles. [1] Typically the fingers, and, less commonly, the toes, are involved. [ 1 ]
Raynaud's phenomenon is frequently the first manifestation of CREST/lcSSc, preceding other symptoms by years. Stress and cold temperature induce an exaggerated vasoconstriction of the small arteries, arterioles, and thermoregulatory vessels of the skin of the digits. Clinically this manifests as a white-blue-red transition in skin color.
Raynaud's normally affects the fingers and toes. Systemic scleroderma and Raynaud's can cause painful ulcers on the fingers or toes, which are known as digital ulcers. Calcinosis (deposition of calcium in lumps under the skin) is also common in systemic scleroderma, and is often seen near the elbows, knees, or other joints. [6] Musculoskeletal
In people with Raynaud’s phenomenon, cold temperatures or stress trigger spasms in the small blood vessels near the surface of the skin, causing the vessels to constrict and limit blood flow.
Raynaud's phenomenon (also known as Raynaud's disease or syndrome) is an important condition affecting skin temperature of many around the globe. [35] Raynaud's phenomenon is the exaggerated response of cutaneous circulation to exposure to cold ambient temperatures. [36] ‘Raynaud attacks’, which can begin in parts of the body and spread ...
The most prevalent skin change is Raynaud's phenomenon, which usually appears early in the course of the disease. [14] Swollen digits are a common sign, and on occasion, the complete hand swells. [ 15 ] [ 16 ] Acrosclerosis , also known as sclerodactyly , can develop with or without proximal scleroderma and is usually a later symptom of the ...
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Skin Progesterone: Probable Extremely rare [4] Autoimmune urticaria: Skin IgG against IgE or IgE receptor: Probable Not well established [5] [6] Bullous pemphigoid: Skin Anti-BP180, Anti-BP230 Confirmed 6-30 per 100,000 (mostly older adults) [7] Cicatricial pemphigoid: Mucous membranes, sometimes skin Anti-BP180, Anti-BP230 Confirmed Rare [8]