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Cilostazol, sold under the brand name Pletal among others, is a medication used to help the symptoms of intermittent claudication in peripheral vascular disease. [2] If no improvement is seen after 3 months, stopping the medication is reasonable. [3] It may also be used to prevent stroke. [2] It is taken by mouth. [2]
[18] [7] Nonsurgical treatments include medications, physical therapy, and spinal injections. Medication options for neurogenic claudication have included non-steroidal anti-inflammatory drugs (NSAIDs), prostaglandin-based drugs, gabapentin, and methylcobalamin. However, the quality of evidence supporting their use is not high enough for ...
The word claudication comes from Latin claudicare 'to limp'. Claudication that appears after a short amount of walking may sometimes be described by US medical professionals by the number of typical city street blocks that the patient can walk before the onset of claudication. Thus, "one-block claudication" appears after walking one block, "two ...
Intermittent claudication, also known as vascular claudication, is a symptom that describes muscle pain on mild exertion (ache, cramp, numbness or sense of fatigue), [1] classically in the calf muscle, which occurs during exercise, such as walking, and is relieved by a short period of rest.
Like other methylated xanthine derivatives, pentoxifylline is a competitive nonselective phosphodiesterase inhibitor [20] which raises intracellular cAMP, activates PKA, inhibits TNF [21] [22] and leukotriene [23] synthesis, and reduces inflammation and innate immunity. [23]
ShutterstockCompound exercises are those significant bang-for-your-buck movements that engage multiple muscle groups simultaneously, helping to accelerate your metabolism and increase fat burning ...
This results in claudication and chronic leg ischemia. This condition mainly occurs more in young athletes than in the elderlies. [ 2 ] Elderlies, who present with similar symptoms, are more likely to be diagnosed with peripheral artery disease with associated atherosclerosis . [ 2 ]
Regular exercise for those with claudication helps open up alternative small vessels (collateral flow), and the limitation in walking often improves. Treadmill exercise (35 to 50 minutes, three or four times per week [ 34 ] ) has been reviewed as another treatment with a number of positive outcomes, including a reduction in cardiovascular ...