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In a 2006 study, a single dose of modafinil 200 mg caused a decrease in blood prolactin levels, although it did not affect human growth hormone or thyroid-stimulating hormone. [87] [143] Since modafinil induces the activity of the CYP3A4 enzyme involved in cortisol clearance, [144] modafinil may reduce the bioavailability of hydrocortisone ...
A Cephalon-founded study in which patients were administered modafinil, methylphenidate, and a placebo found that modafinil produces "psychoactive and euphoric effects and feelings consistent with [methylphenidate]." [12] Like modafinil, armodafinil is an inhibitor and/or inducer of certain cytochrome P450 enzymes.
Chemical structure of modafinil. This page lists chemical compounds similar to modafinil, known as modafinil analogues and derivatives. These are structural analogues and derivatives of modafinil, a drug that affects dopamine levels in the brain in an unusual way (atypical dopamine reuptake inhibitor or DRI).
Modafiendz, also known as N-methyl-4,4-difluoromodafinil or as N-methylbisfluoromodafinil, is a wakefulness-promoting agent related to modafinil that was never marketed. [1] [2] [3] It is sold online and used non-medically as a nootropic (cognitive enhancer).
The clinic also spent nearly $100,000 during that period on Provigil, a stimulant that is “55 times more expensive than the generic equivalent,” the report said.
Typically, the recommended starting dosage for Wellbutrin is 200mg per day, with a maximum dosage of 450mg per day. The starting dosage is taken as 100mg twice per day.
Flmodafinil (CRL-40940, NLS-4, JBG01-41, bisfluoromodafinil, lauflumide) – a bisfluoro-sbustituted derivative of modafinil; Fluorenol ("hydrafinil") – a novel eugeroic structurally unrelated to modafinil and its analogues; Modafiendz (methylbisfluoromodafinil) – a methyl and bisfluoro-substituted derivative of modafinil
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