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  2. Raynaud syndrome - Wikipedia

    en.wikipedia.org/wiki/Raynaud_syndrome

    Raynaud syndrome, also known as Raynaud's phenomenon, is a medical condition in which the spasm of small arteries causes episodes of reduced blood flow to end arterioles. [1] Typically the fingers, and, less commonly, the toes, are involved. [ 1 ]

  3. Livedo reticularis - Wikipedia

    en.wikipedia.org/wiki/Livedo_reticularis

    Livedo reticularis is a common skin finding consisting of a mottled reticulated vascular pattern that appears as a lace-like purplish discoloration of the skin. [1] The discoloration is caused by reduction in blood flow through the arterioles that supply the cutaneous capillaries, resulting in deoxygenated blood showing as blue discoloration ().

  4. Systemic scleroderma - Wikipedia

    en.wikipedia.org/wiki/Systemic_scleroderma

    Most patients (over 80%) have vascular symptoms and Raynaud's phenomenon, which leads to attacks of discoloration of the hands and feet in response to cold. Raynaud's normally affects the fingers and toes. Systemic scleroderma and Raynaud's can cause painful ulcers on the fingers or toes, which are known as digital ulcers.

  5. CREST syndrome - Wikipedia

    en.wikipedia.org/wiki/CREST_syndrome

    CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem connective tissue disorder.The acronym "CREST" refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.

  6. Scleroderma - Wikipedia

    en.wikipedia.org/wiki/Scleroderma

    Cardiovascular: Raynaud's phenomenon (is the presenting symptom in 30% of affected persons, occurs in 95% of affected individuals at some time during their illness); healed pitting ulcers on the fingertips; skin and mucosal telangiectasis; palpitations, irregular heart rate and fainting due to conduction abnormalities, hypertension, and ...

  7. Mixed connective tissue disease - Wikipedia

    en.wikipedia.org/wiki/Mixed_connective_tissue...

    The most prevalent skin change is Raynaud's phenomenon, which usually appears early in the course of the disease. [14] Swollen digits are a common sign, and on occasion, the complete hand swells. [15] [16] Acrosclerosis, also known as sclerodactyly, can develop with or without proximal scleroderma and is usually a later symptom of the condition ...

  8. Largest ever genetic study of Raynaud's phenomenon ... - AOL

    www.aol.com/news/study-pinpoints-genes-behind...

    Raynaud’s phenomenon, which causes parts of the body like the fingers and the toes to go cold and numb, likely stems from two genes, a study published Thursday in the journal Nature ...

  9. Livedoid vasculopathy - Wikipedia

    en.wikipedia.org/wiki/Livedoid_vasculopathy

    Livedoid vasculopathy (LV) is an uncommon thrombotic dermal vasculopathy that is characterized by excruciating, recurrent ulcers on the lower limbs. [4] Livedo racemosa, along with painful ulceration in the distal regions of the lower extremities, is the characteristic clinical appearance.