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Negative-strand RNA viruses (−ssRNA viruses) are a group of related viruses that have negative-sense, single-stranded genomes made of ribonucleic acid (RNA). They have genomes that act as complementary strands from which messenger RNA (mRNA) is synthesized by the viral enzyme RNA-dependent RNA polymerase (RdRp). During replication of the ...
Viruses of the family Orthomyxoviridae contain six to eight segments of linear negative-sense single stranded RNA. They have a total genome length that is 10,000–14,600 nucleotides (nt). [7] The influenza A genome, for instance, has eight pieces of segmented negative-sense RNA (13.5 kilobases total). [8]
In contrast, purified RNA of a negative-sense virus is not infectious by itself as it needs to be transcribed into positive-sense RNA; each virion can be transcribed to several positive-sense RNAs. Ambisense RNA viruses resemble negative-sense RNA viruses, except they translate genes from their negative and positive strands. [6]
Paramyxoviridae (from Greek para-“by the side of” and myxa “mucus”) is a family of negative-strand RNA viruses in the order Mononegavirales. [1] [2] Vertebrates serve as natural hosts. [3] Diseases associated with this family include measles, mumps, and respiratory tract infections. [4]
Rhabdoviridae is a family of negative-strand RNA viruses in the order Mononegavirales. [1] ... This in turn is used to produce more negative-sense genomic RNA. The ...
Bunyaviruses have three single-stranded RNA (ssRNA) fragments, some of them containing both positive-sense and negative-sense sections; arenaviruses are also ssRNA viruses with an ambisense genome, as they have three fragments that are mainly negative-sense except for part of the 5′ ends of the large and small segments of their genome.
Filoviridae (/ ˌ f aɪ l oʊ ˈ v ɪr ɪ d iː / [1]) is a family of single-stranded negative-sense RNA viruses in the order Mononegavirales. [2] Two members of the family that are commonly known are Ebola virus and Marburg virus.
Phenuiviridae is a family of negative-strand RNA viruses in the order Bunyavirales. [1] Ruminants, camels, humans, and mosquitoes serve as natural hosts.Until 2011, member genus Phlebovirus was the only genus of the family with viruses causing disease in humans (e.g. Rift Valley fever virus) [2] [scientific citation needed] except Dabie bandavirus.