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The blood–ocular barrier is a barrier created by endothelium of capillaries of the retina and iris, ciliary epithelium and retinal pigment epithelium. [1] It is a physical barrier between the local blood vessels and most parts of the eye itself, and stops many substances including drugs from traveling across it. [2]
The macula responsible for central vision and the anterior part of the optic nerve are dependent on choroidal blood supply. [4] The structure of choroidal vessels can be revealed by optical coherence tomography, and blood flow can be revealed by Indocyanine green angiography, and laser Doppler imaging. [5]
The uvea (/ ˈ j uː v i ə /; [1] derived from Latin: uva meaning "grape"), also called the uveal layer, uveal coat, uveal tract, vascular tunic or vascular layer, is the pigmented middle layer of the three concentric layers that make up an eye, precisely between the inner retina and the outer fibrous layer composed of the sclera and cornea.
The innermost is the retina, which gets its oxygenation from the blood vessels of the choroid (posteriorly) as well as the retinal vessels (anteriorly). The spaces of the eye are filled with the aqueous humour anteriorly, between the cornea and lens, and the vitreous body , a jelly-like substance, behind the lens, filling the entire posterior ...
The optic disc in a normal human eye carries 1–1.2 million afferent nerve fibers from the eye toward the brain. The optic disc is also the entry point for the major arteries that supply the retina with blood, and the exit point for the veins from the retina. [1]
It is secreted from the ciliary body, a structure supporting the lens of the eyeball. [1] It fills both the anterior and the posterior chambers of the eye, and is not to be confused with the vitreous humour, which is located in the space between the lens and the retina, also known as the posterior cavity or vitreous chamber. [2]
The anterior chamber is the aqueous humor-filled space inside the eye between the iris and the cornea's innermost surface, the endothelium. [1] Hyphema, anterior uveitis and glaucoma are three main pathologies in this area. In hyphema, blood fills the anterior chamber as a result of a hemorrhage, most commonly after a blunt eye injury.
Fluorescein angiography is used by physicians specializing in the treatment of eye diseases (ophthalmologists) to evaluate the vasculature of the retina, choroid, optic disc, and iris. [3] Among the common groups of ophthalmologic disease, fluorescein angiography can detect diabetic retinopathy ( neovascularization ), vein occlusions, retinal ...