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  2. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    This metabolite also has an affinity for the PDE receptors, about 40% of that of sildenafil. Thus, the metabolite is responsible for about 20% of sildenafil's action. Sildenafil is excreted as metabolites predominantly in the feces (about 80% of administered oral dose) and to a lesser extent in the urine (around 13% of the administered oral dose).

  3. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Whether you’re one of the 30 million men who have (ED) or not, you’ve almost certainly heard of Viagra. Maybe you even know about other ED medications, like Levitra or Stendra or Cialis, too.

  4. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  5. 4 Common ED Pills: Weighing the Pros & Cons of Each - AOL

    www.aol.com/4-common-ed-pills-weighing-141800609...

    Its long duration means side effects could last longer than with other ED pills. Tadalafil Pros Tadalafil has a half-life of 17.5 hours — it remains active in your body for far longer than other ...

  6. Viagra: What It Treats & Its Side Effects ( Plus What It Was ...

    www.aol.com/viagra-treats-side-effects-plus...

    Likewise, Viagra shouldn’t be combined with antiretroviral drugs used to treat HIV/AIDS, as it can cause an increased concentration of sildenafil in the body. Breastfeeding women shouldn’t ...

  7. How to Take Viagra for Best Results - AOL

    www.aol.com/viagra-best-results-105700318.html

    When to Take Viagra: 30-60 Minutes Before Intimacy, Not Earlier. If you’re planning to have intimacy, it’s best to take your recommended dose of Viagra ahead of time.

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