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The test was once part of the World Health Organization (WHO) algorithm for diagnosis of dengue fever, [3] however it is no longer used in the latest WHO guidance. [4] Studies have shown that the tourniquet test has low predictive value for dengue fever and should be used in conjunction with other tests for a reliable diagnosis. [5] [6] [7] [8]
Dengue can also be transmitted via infected blood products and through organ donation. [21] [22] In countries such as Singapore, where dengue is endemic, the risk is estimated to be between 1.6 and 6 per 10,000 transfusions. [23] Vertical transmission (from mother to child) during pregnancy or at birth has been reported. [24]
Mild cases of dengue fever can easily be confused with several common diseases including Influenza, measles, chikungunya, and zika. [61] [62] Dengue, chikungunya and zika share the same mode of transmission (Aedes mosquitoes) and are often endemic in the same regions, so that it is possible to be infected simultaneously by more than one disease ...
Over the last twenty years, there has been a geographic spread of the disease. Dengue incidence rates have risen sharply within urban areas which have recently become endemic hot spots for the disease. [57] The recent spread of Dengue can also be attributed to rapid population growth, increased coagulation in urban areas, and global travel.
Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
Dengue is a Flaviviridae virus, with five genetic types. [8] [9] Here is the virus drawn as a 3-dimensional model of the envelope protein. [10]Dengue is in the same family as other well known viruses carried by mosquitoes that cause tropical diseases, such as yellow fever, West Nile, and Zika virus.
A median of 288 days (274 days from the date of ovulation) for first-time mothers and 283 days (269 days from the date of ovulation) for mothers with at least one previous pregnancy was found by a 1990 study of 114 white, private-care patients with uncomplicated pregnancies and spontaneous labor. The authors suggest that excluding pregnancies ...
Dengue vaccine is a vaccine used to prevent dengue fever in humans. [9] Development of dengue vaccines began in the 1920s, but was hindered by the need to create immunity against all four dengue serotypes. [10] As of 2023, there are two commercially available vaccines, sold under the brand names Dengvaxia and Qdenga. [11] [12]
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