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The black mamba (Dendroaspis polylepis) is a species of highly venomous snake belonging to the family Elapidae.It is native to parts of sub-Saharan Africa.First formally described by Albert Günther in 1864, it is the second-longest venomous snake after the king cobra; mature specimens generally exceed 2 m (6 ft 7 in) and commonly grow to 3 m (9.8 ft).
A single dendrotoxin molecule associates reversibly with a potassium channel in order to exert its inhibitory effect. It is proposed that this interaction is mediated by electrostatic interactions between the positively charged amino acid residues in the cationic domain of dendrotoxin and the negatively charged residues in the ion channel pore.
Acute kidney injury has been reported in a few cases of black mamba bites in humans as well as in animal models. [17] Death is due to suffocation resulting from paralysis of the respiratory muscles. [17] [42] Untreated black mamba bites have a mortality rate of 100%. [17] [43] Antivenom therapy is the mainstay of treatment for black mamba ...
A venomous black mamba snake hid under a braai, or grill, in Westville, Durban, providing a homeowner with an frightening sight after they opened its lid.After being called to the scene on ...
Calciseptine has been shown to specifically inhibit the L-type voltage-gated Ca 2+ channels and was the first natural polypeptide discovered with this property. Specific polypeptide inhibitors of voltage-sensitive channels are important tools in research, and were already known for voltage-sensitive Na + channels, both voltage-sensitive and Ca 2+-activated K + channels, and for N-type Ca 2 ...
The effect of the venom of proteroglyphous snakes (sea snakes, kraits, mambas, black snakes, tiger snakes, and death adders) is mainly on the nervous system, respiratory paralysis being quickly produced by bringing the venom into contact with the central nervous mechanism that controls respiration; the pain and local swelling that follow a bite ...
In this latest study, the researchers used a toxin from the venom of a green mamba snake to identify and locate a receptor protein, M1R, on oligodendrocyte precursor cells (OPCs), which fail to ...
"The Mandela Effect is a pervasive false memory where people are very confident about a memory they have that's incorrect," Bainbridge tells Yahoo. It's often associated with pop culture.