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  2. Clopidogrel - Wikipedia

    en.wikipedia.org/wiki/Clopidogrel

    Clopidogrel, sold under the brand name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. [10] It is also used together with aspirin in heart attacks and following the placement of a coronary artery stent ( dual antiplatelet therapy ). [ 10 ]

  3. Adenosine diphosphate receptor inhibitor - Wikipedia

    en.wikipedia.org/wiki/Adenosine_diphosphate...

    Metabolism of ticlopidine, clopidogrel and prasugrel to an active metabolite. Clopidogrel is a prodrug that is metabolized by two pathways. In one of the pathway most of the dose of clopidogrel (85%) is hydrolyzed by esterases to an inactive carboxylic acid derivate and rapidly cleared via glucoridination followed by renal excretion.

  4. Prasugrel - Wikipedia

    en.wikipedia.org/wiki/Prasugrel

    Discontinuing clopidogrel 75 mg and initiating prasugrel 10 mg with the next dose resulted in increased inhibition of platelet aggregation, but not greater than that typically produced by a 10-mg maintenance dose of prasugrel alone. Increasing platelet inhibition could increase bleeding risk.

  5. Dosage (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Dosage_(pharmacology)

    Dosage typically includes information on the number of doses, intervals between administrations, and the overall treatment period. [3] For example, a dosage might be described as "200 mg twice daily for two weeks," where 200 mg represents the individual dose, twice daily indicates the frequency, and two weeks specifies the duration of treatment.

  6. Commonly prescribed drugs - Wikipedia

    en.wikipedia.org/wiki/Commonly_prescribed_drugs

    Rash (Clopidogrel) Dual antiplatelet therapy with aspirin for a reduction of risk of major adverse cardiac events for all acute coronary syndrome patients [24] An image of clopidogrel tablet package (Plavix) Caution. Metabolism of P2Y12 inhibitors requires CYP450 enzymes → potential drug interactions; Contraindications. Prasugrel Stroke

  7. 6 Signs Wellbutrin is Right for Your Depression Symptoms - AOL

    www.aol.com/6-signs-wellbutrin-depression...

    It’s normal to try several antidepressants before finding the optimal one for you, and in some cases, Wellbutrin may not be that one. Look for the following signs that Wellbutrin isn’t working:

  8. Drug intolerance - Wikipedia

    en.wikipedia.org/wiki/Drug_intolerance

    In other words, in a person that is intolerant to a medication, it is possible for a dose of 10 mg to "feel" like a dose of 100 mg, resulting in an overdose—a "normal" dose can be a "toxic" dose in these individuals, leading to clinically significant effects. There is also an aspect of drug intolerance that is subjective.

  9. Lisa Marie Presley's memoir completed after her death reveals ...

    www.aol.com/lisa-marie-presleys-memoir-completed...

    As Keough explains in the memoir, these new drugs "only served to make her even more high because whatever the normal dose was, she would somehow get five times that amount from the doctors."

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