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Multilocular cystic renal cell carcinoma (MCRCC) is rare subtype of renal cell carcinoma. Histologically, the tumor has a fibrous capsule and contains multiple cysts with clear cells. [1] 1-5% of renal cell carcinomas are MCRCC. [1]
On renal ultrasonography, a solid renal mass appears in the US exam with internal echoes, without the well-defined, smooth walls seen in cysts, often with Doppler signal, and is frequently malignant or has a high malignant potential. The most common malignant renal parenchymal tumor is renal cell carcinoma (RCC), which accounts for 86% of the ...
High magnification micrograph of a cystic nephroma showing the characteristic simple epithelium with hobnail morphology, and the ovarian-like stroma. H&E stain. The characteristics of cystic nephromas are: Cysts lined by a simple epithelium with a hobnail morphology, i.e. the nuclei of the cyst lining epithelium bulges into the lumen of the cysts,
Deciding on the benign or malignant nature of the renal mass on the basis of its localized size is an issue as renal cell carcinoma may also be cystic. As there are several benign cystic renal lesions (simple renal cyst, haemorrhagic renal cyst, multilocular cystic nephroma , polycystic kidney disease ), it may occasionally be difficult for the ...
Kidney cancer, also known as renal cancer, is a group of cancers that starts in the kidney. [4] Symptoms may include blood in the urine, a lump in the abdomen, or back pain. [1] [2] [3] Fever, weight loss, and tiredness may also occur. [1] [2] [3] Complications can include spread to the lungs or brain. [6]
Normal kidney is seen on the left of the image. Kidney biopsy. PAS stain. Metanephric adenoma is diagnosed histologically. The tumours can be located at upper pole, lower pole and mid-hilar region of the kidney; they are well circumscribed but unencapsulated, tan pink, with possible cystic and hemorrhagic foci.
Potentially-malignant neoplasms include carcinoma in situ. They are localised, and do not invade and destroy but in time, may transform into cancer. Malignant neoplasms are commonly called cancer. They invade and destroy the surrounding tissue, may form metastases and, if untreated or unresponsive to treatment, will generally prove fatal.
Post-operatively, the presence of renin granules in pathology specimens as well as immunohistochemical analyses could help differentiating this tumor from other primary renal tumors such as hemangiopericytoma, glomus tumor, metanephric adenoma, epithelioid angiomyolipoma, Wilms tumor, solitary fibrous tumor, and some epithelial neoplasms. [6] [8]