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Off-label use is the use of pharmaceutical drugs for an unapproved indication or in an unapproved age group, dosage, or route of administration. [1] Both prescription drugs and over-the-counter drugs (OTCs) can be used in off-label ways, although most studies of off-label use focus on prescription drugs.
You may notice sudden hair loss, gradual hair loss, or hair loss that gets better or worse over time. Essentially, alopecia in women can look quite different from one person to the next. Common ...
Take Wegovy, for example: In those clinical trials, only three percent of adults reported hair loss as an adverse reaction versus one percent on a placebo (hair loss was not a reported side effect ...
Hair loss is part of the natural three-phase hair growth cycle, which involves the anagen (growth) phase, the catagen (declining) phase and the telogen (resting) phase.
[27] [28] [29] While used off-label for male pattern hair loss in most of the world, dutasteride is specifically approved for this indication in South Korea and Japan. [30] [31] There is tentative support for spironolactone in women. [14] Due to its feminising side effects and risk of infertility it is not often used by men.
Other 5α-reductase inhibitors such as finasteride (a type 2 inhibitor) have been used off-label to treat excessive hair growth in women with hirsutism. [ 3 ] [ 23 ] Since dutasteride is an inhibitor of both type 1 and 2 5α-reductases, it could theoretically be a more effective therapy for hirsutism.
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