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The descent of the testicles consists of the opening of a connection from the testis to its final location at the anterior abdominal wall, followed by the development of the gubernaculum, which subsequently pulls and translocates the testicle down into the developing scrotum. Ultimately, the passageway closes behind the testis.
According to this concept, testicular descent status is "set" during the period from 8 to 14 weeks of gestation in humans. Undescended testis is a result of disruption in androgen levels only during this programming window. [14]
[5] [6] [7] The evolutionary adaptive advantage of testicular descent into an extra-abdominal position may be related more to the enhanced sperm storage capacity of the epididymis at lower extra-abdominal temperatures than to the testis itself. [7] Greater sperm storage capacity in the epididymis has been associated with enhanced fertility.
A testicle or testis (pl. testes) is the gonad in all male bilaterians, including humans, and is homologous to the ovary in ... Testes follow the path of descent, ...
As the scrotum and labia majora form in males and females respectively, the gubernaculum aids in the descent of the gonads (both testes and ovaries). [3] The testes descend to a greater degree than the ovaries and ultimately pass through the inguinal canal into the scrotum. [3] The mechanism of this movement is still debated. [3]
Via the rete testis, the seminiferous tubules become connected with outgrowths from the mesonephros, which form the efferent ducts of the testicle. In short, the descent of the testicles consists of the opening of a connection from the testicle to its final location at the anterior abdominal wall, followed by the development of the gubernaculum ...
The tunica vaginalis is derived from the vaginal process of the peritoneum, which in the fetus precedes the descent of the testes from the abdomen into the scrotum. [7] The vaginal process between the abdominal inguinal ring and the superior part of the testis is then obliterated, usually leaving a string-like or cord-like remnant adjacent to ...
These cells then induce the production and organisation of cells making up the testicular cords. [2] These cords will eventually become the testes, which in turn produce hormones, in particular testosterone. [8] These hormones drive the formation of the other male sex characteristics, and induce testicular descent out of the abdomen. [4]