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Hypersalivation can contribute to drooling if there is an inability to keep the mouth closed or difficulty in swallowing (dysphagia) the excess saliva, which can lead to excessive spitting. Hypersalivation also often precedes emesis (vomiting), where it accompanies nausea (a feeling of needing to vomit).
Artificial saliva is primarily used to relieve symptoms of xerostomia, known as dry mouth and hyposalivation, which is a condition that results in reduced saliva production. Various factors, including medication use, cancer therapy , and certain diseases, such as diabetes , stroke or Sjögren syndrome , can cause xerostomia. [ 1 ]
A 1:20 solution is isotonic with body fluids. 1:4 dilution is used for wound management applications; this contains 0.25% (w/v) available chlorine and has a pH of 10.5–11.2 . [ 1 ] [ 2 ] The fluid has been used in endodontics , for example to irrigate an infected root canal , although it is not medically licensed for use in the mouth.
Drooling can be caused by excess production of saliva, inability to retain saliva within the mouth (incontinence of saliva), or problems with swallowing (dysphagia or odynophagia). There are some frequent and harmless cases of drooling – for instance, a numbed mouth from either benzocaine , or when going to the dentist's office.
Scopolamine, also known as hyoscine, [9] or Devil's Breath, [10] is a natural or synthetically produced tropane alkaloid and anticholinergic drug that is used as a medication to treat motion sickness [11] and postoperative nausea and vomiting.
The function of the salivary glands is to secrete saliva, which has a lubricating function, which protects the mucosa of the mouth during eating and speaking. [2] Saliva also contains digestive enzymes (e.g. salivary amylase), has antimicrobial action, and acts as a buffer. [3]
Clonazepam ODT blister pack and tablet Etizest-1 MD (Etizest-brand 1mg-doskk etizolam mouth-dissolving (MD) blister pack and opened tablet. An orally disintegrating tablet or orally dissolving tablet (ODT) is a drug dosage form available for a limited range of over-the-counter (OTC) and prescription medications.
The lethal dose for most adult humans is estimated at 5 to 10 grams, equivalent to 32 to 64 mg elemental fluoride per kg of body weight. [ 17 ] [ 18 ] [ 19 ] Ingestion of fluoride can produce gastrointestinal discomfort at doses as low as 0.2 mg/kg, 20 times lower than lethal doses. [ 20 ]