Search results
Results from the WOW.Com Content Network
The AIFM2 gene encodes the FSP1 protein encoded by this gene has significant homology to NADH oxidoreductases and the apoptosis-inducing factor PDCD8/AIF.Although it was originally proposed that this protein induce apoptosis due to its similarity with AIF, findings from James Olzmann's group at UC Berkeley [10] and Marcus Conrad's group at the Helmholtz Institute [9] demonstrated that the ...
The gene atf2 is located at human chromosome 2q32. [6] The protein ATF-2 has 505 amino acids. Studies in mice indicate a role for ATF-2 in the development of nervous system and the skeleton. [7] ATF-2 is normally activated in response to signals that converge on stress-activated protein kinases p38 and JNK. [8]
The ZFPM2 gene is found in a wide range of animal species from flies to humans. The human gene is located on the long or "q" arm of chromosome 8 at position 23.1 (i.e. 8q23.1) and consists of 9 exons. [10] The equivalent mouse gene, Zfpm2, is located on chromosome 15 and consists of 8 exons. [11]
WRKY transcription factors (pronounced ‘worky’) are proteins that bind DNA.They are transcription factors that regulate many processes in plants and algae (Viridiplantae), such as the responses to biotic and abiotic stresses, senescence, seed dormancy and seed germination and some developmental processes [1] [2] but also contribute to secondary metabolism.
And the splicing factor can be divided into snRNP and non snRNP proteins.U2 auxiliary factor , composed of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit, which contains a sequence-specific RNA-binding region with 3 RNA recognition ...
Nuclear factor erythroid 2-related factor 2 (NRF2), also known as nuclear factor erythroid-derived 2-like 2, is a transcription factor that in humans is encoded by the NFE2L2 gene. [5] NRF2 is a basic leucine zipper (bZIP) protein that may regulate the expression of antioxidant proteins that protect against oxidative damage triggered by injury ...
T-box transcription factor 2 Tbx2 is a transcription factor that is encoded by the Tbx2 gene on chromosome 17q21-22 in humans. [ 5 ] [ 6 ] [ 7 ] This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box .
Eukaryotic translation initiation factor 2-alpha kinase 3, also known as protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK), is an enzyme that in humans is encoded by the EIF2AK3 gene. [5] [6] [7] [8]