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Flucloxacillin, also known as floxacillin, is an antibiotic used to treat skin infections, external ear infections, infections of leg ulcers, diabetic foot infections, and infection of bone. [6] It may be used together with other medications to treat pneumonia , and endocarditis . [ 6 ]
The package leaflet supplied with the product is aimed at end-users. [3] A cartoon by Roy Doty depicting the package insert as overly long and complicated. In the United States, the Food and Drug Administration (FDA) determines the requirements for patient package inserts.
Ampicillin/flucloxacillin also known as co-fluampicil (), and sold under the tradename Magnapen, is a combination drug of the two β-lactam antibiotics, ampicillin and flucloxacillin, both in equal amounts, available in a capsule and as a liquid, both taken by mouth, and as a formulation which can be given by injection into muscle or vein.
Cloxacillin is an antibiotic useful for the treatment of several bacterial infections. [1] This includes impetigo, cellulitis, pneumonia, septic arthritis, and otitis externa. [1]
β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.
Another condition in which antibiotics are indicated is staphylococcal mucositis and it is mostly found in immunocompromised patients and the elderly. [2] Patients will experience oral discomfort, mucosal inflammation and mucosal bleeding. The common treatment for this type of infection is oral lavages and flucloxacillin. [2]
Some patients may benefit from systemic narrow-spectrum penicillinase-resistant penicillins (such as dicloxacillin in the US or flucloxacillin in UK). Fungal folliculitis may require an oral antifungal such as fluconazole. Topical antifungals such as econazole nitrate may also be effective. [1] Folliculitis may recur even after symptoms have ...
Of patients with documented penicillin allergy, approximately 95% will return a negative penicillin skin-prick test [11] but patients carrying a penicillin allergy label are significantly more likely to experience worse outcomes. [12]