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  2. Raynaud syndrome - Wikipedia

    en.wikipedia.org/wiki/Raynaud_syndrome

    Patients with secondary Raynaud's can also have symptoms related to their underlying diseases. Raynaud's phenomenon is the initial symptom that presents for 70% of patients with scleroderma, a skin and joint disease. [citation needed] When Raynaud's phenomenon is limited to one hand or one foot, it is referred to as unilateral Raynaud's.

  3. Mixed connective tissue disease - Wikipedia

    en.wikipedia.org/.../Mixed_connective_tissue_disease

    The most prevalent skin change is Raynaud's phenomenon, which usually appears early in the course of the disease. [14] Swollen digits are a common sign, and on occasion, the complete hand swells. [15] [16] Acrosclerosis, also known as sclerodactyly, can develop with or without proximal scleroderma and is usually a later symptom of the condition ...

  4. Moxisylyte - Wikipedia

    en.wikipedia.org/wiki/Moxisylyte

    Moxisylyte, also known as thymoxamine, is a drug used in urology for the treatment of erectile dysfunction. [1] It is an α 1-adrenergic antagonist. [2] In the United Kingdom, Moxisylte is marketed as Opilon (Archimedes Pharma UK Ltd) and is used for the short-term treatment of primary Raynaud's syndrome.

  5. Prostacyclin receptor - Wikipedia

    en.wikipedia.org/wiki/Prostacyclin_receptor

    [17] [19] [20] However, newly developed IP agonists with favorable pharmacological features such as Selexipag have been granted by the US FDA orphan drug status for the treatment of pulmonary hypertension. IP agonists are also to treat severe vasoconstriction in Raynaud's disease, Raynaud's disease-like syndromes, and scleroderma.

  6. Largest ever genetic study of Raynaud's phenomenon ... - AOL

    www.aol.com/news/study-pinpoints-genes-behind...

    Raynaud’s phenomenon, which causes parts of the body like the fingers and the toes to go cold and numb, likely stems from two genes, a study published Thursday in the journal Nature ...

  7. Scleroderma - Wikipedia

    en.wikipedia.org/wiki/Scleroderma

    No cure for scleroderma is known, although relief of symptoms is often achieved; these include treatment of: [13] [32] Raynaud's phenomenon with vasodilators such as calcium channel blockers, alpha blockers, serotonin receptor antagonists, angiotensin II receptor inhibitors, statins, local nitrates or iloprost

  8. Learn More About 10 Rare Diseases Worthy Of More Attention - AOL

    www.aol.com/learn-more-10-rare-diseases...

    In addition to hard leathery patches of skin, joint pain, fatigue and Raynaud’s syndrome are common. 10. Thyroid eye disease. A person with thyroid eye disease will notice progressively worse ...

  9. Nicergoline - Wikipedia

    en.wikipedia.org/wiki/Nicergoline

    It is used for vascular disorders such as cerebral thrombosis and atherosclerosis, arterial blockages in the limbs, Raynaud's disease, vascular migraines, and retinopathy. Nicergoline has been registered in over fifty countries and has been used for more than three decades for the treatment of cognitive, affective, and behavioral disorders of ...