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TOL-463 is an anti-infective medication which is under development for the treatment of bacterial vaginosis (BV) and vulvovaginal candidiasis (VVC) (vaginal yeast infection). [ 3 ] [ 1 ] [ 4 ] [ 2 ] It is a boric acid -based vaginal anti-infective enhanced with ethylenediaminetetraacetic acid (EDTA) which was designed to have improved activity ...
Bacterial vaginosis (BV) is an infection of the vagina caused by excessive growth of bacteria. [ 6 ] [ 12 ] Common symptoms include increased vaginal discharge that often smells like fish. [ 2 ] The discharge is usually white or gray in color. [ 2 ]
Patients should be advised to avoid sexual intercourse for at least 1 week and until they and their partner(s) have completed treatment and follow-up." [32] Bacterial vaginosis: The most commonly used antibiotics are metronidazole, available in both pill and gel form, and clindamycin available in both pill and cream form. [11]
Bacterial vaginosis (BV) is the most common vaginal infection in women. According to the Centers for Disease Control and Prevention (CDC), the condition affects nearly 30% of women between 15 and ...
The flora serves as a defense against the invasion and colonization of opportunistic pathogens including bacterial vaginosis, fungi, viruses, and protozoa. [23] Historically, it was believed that the bacterium Gardnerella caused bacterial vaginosis, but studies have shown that bacterial vaginosis can be caused by a variety of bacteria. [ 24 ]
Structurally it actually methyl-metronidazole. Effectiveness in the treatment of dientamoebiasis has been reported. [1] It has also been tested against Atopobium vaginae. [2] In the United States, secnidazole is FDA approved for the treatment of bacterial vaginosis and trichomoniasis in adult women. [3]
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