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Dapagliflozin is an example of an SGLT-2 inhibitor, it is a competitive, highly selective inhibitor of SGLT. It acts via selective and potent inhibition of SGLT-2, and its activity is based on each patient's underlying blood sugar control and kidney function. The results are decreased kidney reabsorption of glucose, glucosuria effect increases ...
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[2] [3] SGLT1, encoded by the SLC5A1 gene, is primarily expressed in the late proximal tubule (S3 segment) and accounts for the remaining 3% of glucose reabsorption. [2] [3] In addition to SGLT1 and SGLT2, there are 10 other members in the human protein family SLC5A. [4] SLC5A4, also known as SGLT3, is a member of the sodium-glucose ...
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Assetto Corsa Competizione (Italian for "race setup", "competition") is a sim racing video game developed by Italian video game developer Kunos Simulazioni.The game focuses on GT3, GT4, GT2 and one make series cars and is an officially licensed simulation of the GT World Challenge Europe and the Total 24 Hours of Spa covering seasons from 2018 to 2023, and is set to serve as a platform for ...
SGLT2 is a member of the sodium glucose cotransporter family, which are sodium-dependent glucose transport proteins. SGLT2 is the major cotransporter involved in glucose reabsorption in the kidney. [6] SGLT2 is located in the early proximal tubule, and is responsible for reabsorption of 80-90% of the glucose filtered by the kidney glomerulus. [7]
2022 ACC Men's Basketball All-Conference Teams: First Team Second Team Third Team Honorable Mention Armando Bacot – North Carolina Alondes Williams – Wake Forest Paolo Banchero – Duke Kameron McGusty – Miami Buddy Boeheim – Syracuse Keve Aluma – Virginia Tech Dereon Seabron – NC State Wendell Moore Jr. – Duke Blake Wesley ...