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Fissure is a lesion in the skin that is usually narrow but deep. [29] [33] Induration is dermal thickening causing the cutaneous surface to feel thicker and firmer. [29] Atrophy refers to a loss of skin, and can be epidermal, dermal, or subcutaneous. [30] With epidermal atrophy, the skin appears thin, translucent, and wrinkled. [29]
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
Nevus (pl.: nevi) is a nonspecific medical term for a visible, circumscribed, chronic lesion of the skin or mucosa. [1] The term originates from nævus, which is Latin for "birthmark"; however, a nevus can be either congenital (present at birth) or acquired. Common terms, including mole, birthmark, and beauty mark, are used to describe nevi ...
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A mole can be either subdermal (under the skin) or a pigmented growth on the skin, formed mostly of a type of cell known as a melanocyte. The high concentration of the body's pigmenting agent, melanin, is responsible for their dark color. Moles are a member of the family of skin lesions known as nevi (singular "nevus"), occurring commonly in ...
List of genes mutated in pigmented cutaneous lesions; List of histologic stains that aid in diagnosis of cutaneous conditions; List of human leukocyte antigen alleles associated with cutaneous conditions; List of immunofluorescence findings for autoimmune bullous conditions; List of inclusion bodies that aid in diagnosis of cutaneous conditions
Skin ulcers appear as open craters, often round, with layers of skin that have eroded. The skin around the ulcer may be red, swollen, and tender. Patients may feel pain on the skin around the ulcer, and fluid may ooze from the ulcer. In some cases, ulcers can bleed and, rarely, patients experience fever. Ulcers sometimes seem not to heal ...
Various differential diagnoses of pigmented skin lesions, including dysplastic nevus, showing the relative incidence of biopsied lesions, and malignancy potential. When an atypical mole has been identified, a skin biopsy takes place in order to best diagnose it. Local anesthetic is used to numb the area, then the mole is biopsied.