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Hypothyroidism (also called underactive thyroid, low thyroid or hypothyreosis) is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormones. [3] It can cause a number of symptoms, such as poor ability to tolerate cold , extreme fatigue, muscle aches , constipation , slow heart rate , depression , and ...
Myxedema coma is an extreme or decompensated form of hypothyroidism and while uncommon, is potentially lethal. [1] [2] [3] A person may have laboratory values identical to a "normal" hypothyroid state, but a stressful event (such as an infection, myocardial infarction, or stroke) precipitates the myxedema coma state, usually in the elderly.
[5] [8] Risk factors include a family history of the condition and having another autoimmune disease. [3] Diagnosis is confirmed with blood tests for TSH, Thyroxine (T 4), antithyroid autoantibodies, and ultrasound. [3] Other conditions that can produce similar symptoms include Graves' disease and nontoxic nodular goiter. [6]
This might include thyroid conditions, malnutrition, or low blood sugar, he explains. ... One potentially life-threatening example is meningitis, which can cause chills with or without a fever ...
“Graves’ disease is an autoimmune condition that stimulates the receptors on the thyroid gland to make more thyroid hormones,” Dr. Deena Gupta ... it can be life-threatening,” Adimoolam ...
Thyrotoxic periodic paralysis (TPP) is a rare condition featuring attacks of muscle weakness in the presence of hyperthyroidism (overactivity of the thyroid gland). Hypokalemia (a decreased potassium level in the blood) is usually present during attacks.
Levothyroxine, a drug used to treat hypothyroidism, can lead to reduced bone mass and density in older adults with normal thyroid levels, a small cohort study has shown.
As a life-threatening medical emergency, thyroid storm has a mortality rate of up to 25% despite treatment. [1] [7] Without treatment, the condition is typically fatal, with a mortality rate of 80-100%. [8] Historically, the condition was considered untreatable, with hospital mortality rates approaching 100%. [9] [10]