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High-resolution CT scan: diffuse pulmonary nodules 4–10 mm, greater than 20 nodules, mosaic attenuation or air trapping in greater than 50% of the lung; Transbronchial biopsy: proliferation of pulmonary neuroendocrine cells; Serum markers: elevated serum chromogranin A levels
For lung nodules, air bronchograms used to be associated with infectious causes of consolidation and, therefore to be benign. However, in the setting of a lung nodule, an air bronchogram is actually more frequent in malignant than in benign nodules. [1] [4] studied the tumour-bronchus relationship and described five types: [1]
Modern detail-oriented scans such as high-resolution computed tomography (HRCT) is the gold standard in respiratory medicine and thoracic surgery for investigating disorders of the lung parenchyma . Contrasted CT scans of the chest are usually used to confirm diagnosis of for lung cancer and abscesses , as well as to assess lymph node status at ...
Lung cancer is the most diagnosed and deadliest cancer worldwide, with 2.2 million cases in 2020 resulting in 1.8 million deaths. [3] Lung cancer is rare in those younger than 40; the average age at diagnosis is 70 years, and the average age at death 72. [2] Incidence and outcomes vary widely across the world, depending on patterns of tobacco use.
Like all methods of radiography, chest radiography employs ionizing radiation in the form of X-rays to generate images of the chest. The mean radiation dose to an adult from a chest radiograph is around 0.02 mSv (2 mrem ) for a front view (PA, or posteroanterior) and 0.08 mSv (8 mrem) for a side view (LL, or latero-lateral). [ 1 ]
Adenocarcinoma of the lung is the most common type of lung cancer, and like other forms of lung cancer, it is characterized by distinct cellular and molecular features. [1] It is classified as one of several non-small cell lung cancers (NSCLC), to distinguish it from small cell lung cancer which has a different behavior and prognosis.
According to the World Health Organization, lung cancer was responsible for approximately 10 million deaths in 2020. [2] The most common cause of lung cancer is long-term exposure to tobacco smoke, and the carcinogens are typically found in cigarettes. [3] In the United States, around 80%-90% of lung cancer deaths are among cigarette smokers. [4]
Non-small-cell lung cancer (NSCLC), or non-small-cell lung carcinoma, is any type of epithelial lung cancer other than small-cell lung cancer (SCLC). NSCLC accounts for about 85% of all lung cancers. [1] [2] [3] As a class, NSCLCs are relatively insensitive to chemotherapy, compared to small-cell carcinoma.