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Acquired generalized lipodystrophy (AGL), also known as Lawrence syndrome [1] and Lawrence–Seip syndrome, [1] is a rare skin condition that appears during childhood or adolescence, characterized by fat loss affecting large areas of the body, particularly the face, arms, and legs.
One study among 96 patients diagnosed with gestational diabetes in the last three years found that, compared to insulin therapy, metformin had superior effects on blood sugar levels, inflammation ...
An MRI image illustrating the lack of subcutaneous fat of a patient with the disease (G) compared to a control patient (A) Specialty: Endocrinology Symptoms: Mild specific body features, absence of subcutaneous fat, muscle hypertrophy, insulin resistance, gigantism/acromegaly, large appetite [1] Complications
Lipodystrophy syndromes are a group of genetic or acquired disorders in which the body is unable to produce and maintain healthy fat tissue. [ 1 ] [ 2 ] The medical condition is characterized by abnormal or degenerative conditions of the body's adipose tissue .
Metformin helps manage blood sugar in people with type 2 diabetes in a few different ways: It helps the body respond better to the insulin it makes naturally, decreases the amount of sugar the ...
Metformin is a biguanide anti-hyperglycemic agent. [16] It works by decreasing glucose production in the liver, increasing the insulin sensitivity of body tissues, [16] and increasing GDF15 secretion, which reduces appetite and caloric intake. [25] [26] [27] [28]
Corticosteroid-induced lipodystrophy (CIL) is a condition of abnormal fat deposition caused by corticosteroid medications. [1] Fat accumulates in the facial area (" moon face "), dorsocervical region ("buffalo hump"), and abdominal area ("pot belly" or "beer belly"), whereas the thickness of subcutaneous fat in the limbs is decreased. [ 1 ]
The type 2 diabetes drug metformin helped slow aging across multiple organs, including the brain, kidneys, and the skin, a study in cynomolgus monkeys has shows. Common diabetes drug may help slow ...