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High doses of caffeine intake during pregnancy may increase the risk of miscarriage [48] and some major negative pregnancy outcomes, such as stillbirth or low birth weight. [ 49 ] [ 50 ] A 2020 review called into question the safe levels proposed by the European Food Safety Authority, the American Congress of Obstetricians and Gynecologists ...
High volume hypernatremia can be due to hyperaldosteronism, excessive administration of intravenous normal saline or sodium bicarbonate, or rarely from eating too much salt. [1] [2] Low blood protein levels can result in a falsely high sodium measurement. [4] The cause can usually be determined by the history of events. [1]
Estimated sodium intake ≥6 g/day and <3 g/day are both associated with high risk of death or major cardiovascular disease, but the association between high sodium intake and adverse outcomes is only observed in people with hypertension. [103]
Low sodium intake level was a mean of <115 mmol (2645 mg), usual sodium intake was 115-215 mmol (2645–4945 mg), and a high sodium intake was >215 mmol (4945 mg), concluding: "Both low sodium intakes and high sodium intakes are associated with increased mortality, consistent with a U-shaped association between sodium intake and health outcomes".
A diet high in sodium increases the risk of hypertension in people with sodium sensitivity, which in turn raises the risk of health issues associated with hypertension including cardiovascular disease. [29] Unfortunately, there is no universally accepted definition of sodium sensitivity, and the methods used to assess it vary across studies.
“The daily recommended sodium intake for children is less than 1,500 mg, and for adults, it's less than 2,300 mg, with even lower limits for those at risk of high blood pressure, dietitian Mimi ...
The mechanism usually stems from compromised regulatory mechanisms for sodium handling as seen in congestive heart failure (CHF), kidney failure, and liver failure. It may also be caused by excessive intake of sodium from foods, intravenous (IV) solutions and blood transfusions , medications, or diagnostic contrast dyes.
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