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Mycobacterium kansasii is a slow-growing, non-tuberculosis mycobacterium (NTM) that, like other mycobacterial species, tends to cause six clinical patterns of infection: pulmonary disease, skin and soft tissue disease, musculoskeletal infections including monoarticular septic arthritis and tenosynovitis, disseminated disease, catheter ...
Mycobacterium kansasii is a bacterium in the Mycobacterium genus. It is an environmental bacteria that causes opportunistic infections in humans, and is one of the leading mycobacterial causes of human disease after tuberculosis and leprosy .
The treatment of lung infections due to M. kansasii and other non-MAC slow growing nontuberculous mycobacteria will be reviewed here. Management of pulmonary infections due to MAC and to rapidly growing mycobacterium (Mycobacterium abscessus, Mycobacterium fortuitum complex, and Mycobacterium chelonae) are discussed separately
Mycobacterium kansasii is an acid-fast bacillus (AFB) that is readily recognized based on its characteristic photochromogenicity, which produces a yellow pigment when exposed to light. In...
The current standard of care therapy for pulmonary Mycobacterium kansasii infection is isoniazid (300 mg/day), rifampin (600 mg/day), and ethambutol (15 mg/kg/day) for 12 months after achieving sputum culture negativity.
Mycobacterium kansasii is one of the most virulent and prevalent NTM pathogen in human medicine. It was first described by Buhler and Pollak in 1953 from a series of respiratory samples of patients with a TB-like pulmonary disease (Buhler and Pollak, 1953).
The incidence of Mycobacterium kansasii varies widely over time and by region, but this organism remains one of the most clinically relevant isolated species of nontuberculous mycobacteria.
Mycobacterium kansasii is the second most common nontuberculous mycobacteria (NTM) after the Mycobacterium avium complex in the United States and Japan, 1, 2 and is the most common cause of NTM lung disease in the United Kingdom and Western Europe. 3, 4 Infection with M. kansasii probably occurs via an aerosol route.
Mycobacterium kansasii, an important opportunistic pathogen of humans, causes serious pulmonary disease. Sixty M. kansasii isolates were collected for investigating the clinical characteristics of patients with M. kansasii infections as well as drug susceptibility and genotypes of M. kansasii.
Mycobacterium kansasii is a non-tuberculosis mycobacterium (NTM) that is readily recognized based on its characteristic photochromogenicity; it produces a yellow pigment when exposed to light. Buhler and Pollack first described this slow-growing mycobacterium in 1953. Under light microscopy, …