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Daratumumab, sold under the brand name Darzalex among others, is an anti-cancer monoclonal antibody medication. It binds to CD38 , [ 7 ] which is overexpressed in multiple myeloma cells. [ 8 ]
Eligible participants were required to have newly diagnosed multiple myeloma and were ineligible for transplant. [2] Efficacy of daratumumab and hyaluronidase-fihj in combination with Rd (D-Rd) was evaluated in a single-arm cohort of this trial. [2] Eligible participants had received at least one prior line of therapy.
Multiple myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. [6] Often, no symptoms are noticed initially. [10] As it progresses, bone pain, anemia, renal insufficiency, and infections may occur. [10]
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The trial assessed Blenrep (belantamab mafodotin) in combination with bortezomib plus dexamethasone (BVd) versus Johnson & Johnson’s (NYSE:JNJ) Darzalex (daratumumab) in combination with ...
Stealing from the private sector's playbook. Fuller said companies have long turned to mass layoffs as a way to reduce costs. Sometimes employees are directed to defend the value they add to the ...
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A North Carolina woman charged in an ATV crash that killed two teenage boys previously worked as a substitute teacher at the victims' school district, a district spokeswoman said Monday.. Ashley ...
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