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An inhalational anesthetic is a chemical compound possessing general anesthetic properties that is delivered via inhalation. They are administered through a face mask, laryngeal mask airway or tracheal tube connected to an anesthetic vaporiser and an anesthetic delivery system .
This seems to be especially problematic in dental anesthesia. [25] Like all the potent inhalational anaesthetic agents, it is a potent trigger for malignant hyperthermia. [5] Similarly, in common with the other potent inhalational agents, it relaxes uterine smooth muscle and this may increase blood loss during delivery or termination of ...
Although having many unwanted side-effects, a slow onset of action and recovery rate it was a big success and at the time the most potent neuromuscular drug available. Pancuronium and some other neuromuscular blocking agents block M2-receptors and therefore affect the vagus nerve , leading to hypotension and tachycardia .
9.1 Inhalational anesthetic agents. 10 See also. Toggle the table of contents. List of medical inhalants. ... Inhalant – non-medical drugs administered via inhalation
Sevoflurane is an inhaled anesthetic that is often used to induce and maintain anesthesia in children for surgery. [17] During the process of awakening from the medication, it has been associated with a high incidence (>30%) of agitation and delirium in preschool children undergoing minor noninvasive surgery. [ 17 ]
The Meyer-Overton correlation for anaesthetics. A nonspecific mechanism of general anaesthetic action was first proposed by Emil Harless and Ernst von Bibra in 1847. [9] They suggested that general anaesthetics may act by dissolving in the fatty fraction of brain cells and removing fatty constituents from them, thus changing activity of brain cells and inducing anaesthesia.
Scopolamine was first written about in 1881 and started to be used for anesthesia around 1900. [ 14 ] [ 15 ] Scopolamine is also the main active component produced by certain plants of the nightshade family , which historically have been used as psychoactive drugs, known as deliriants , due to their antimuscarinic-induced hallucinogenic effects ...
Similar to other local anesthetics, benzonatate is a potent voltage-gated sodium channel blocker. [22] After absorption and circulation to the respiratory tract, benzonatate acts as a local anesthetic, decreasing the sensitivity of vagal afferent fibers and stretch receptors in the bronchi, alveoli, and pleura in the lower airway and lung.