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Regeneration in humans is the regrowth of lost tissues or ... Research suggests that the cell types involved in the process play an important role. ... (heart muscle ...
They are crucial for the repair of muscle, but have a very limited ability to replicate. Activated by stimuli such as injury or high mechanical load, satellite cells are required for muscle regeneration in adult organisms. [3] In addition, satellite cells have the capability to also differentiate into bone or fat. In this way, satellite cells ...
Development and regeneration involves the coordination and organization of populations cells into a blastema, which is "a mound of stem cells from which regeneration begins". [25] Dedifferentiation of cells means that they lose their tissue-specific characteristics as tissues remodel during the regeneration process.
A muscle cell, also known as a myocyte, is a mature contractile cell in the muscle of an animal. [1] In humans and other vertebrates there are three types: skeletal, smooth, and cardiac (cardiomyocytes). [2]
Other vertebrates can regenerate cardiac muscle tissue throughout their entire life span. [7] Skeletal muscle is able to regenerate far better than cardiac muscle due to satellite cells, which are dormant in all healthy skeletal muscle tissue. [8] There are three phases to the regeneration process.
A single satellite cell can proliferate and become a larger amount of muscle cells. [28] With the understanding that myosatellite cells are the progenitor of most skeletal muscle cells, it was theorized that if these cells could be grown in a lab and placed on scaffolds to make fibers, the muscle cells could then be used for food production. [29]
During regeneration, only cartilage cells can form new cartilage tissue, only muscle cells can form new muscle tissue, and so on. The dedifferentiated cells still retain their original specification. [12] To begin the physical formation of a new limb, regeneration occurs in a distal to proximal sequence. [17]
Neuroregeneration is the regrowth or repair of nervous tissues, cells or cell products. Neuroregenerative mechanisms may include generation of new neurons , glia , axons , myelin , or synapses . Neuroregeneration differs between the peripheral nervous system (PNS) and the central nervous system (CNS) by the functional mechanisms involved ...