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[8] [9] Epoetin alfa is an erythropoiesis-stimulating agent. [8] It stimulates erythropoiesis (increasing red blood cell levels) and is used to treat anemia, commonly associated with chronic kidney failure and cancer chemotherapy. Epoetin alfa is developed by Amgen. [8] It is on the World Health Organization's List of Essential Medicines. [10]
Methoxy polyethylene glycol-epoetin beta (Mircera) by Roche [20] epoetin delta: Dynepo trademark name for an erythropoiesis stimulating protein, by Shire plc [21] epoetin omega: Epomax; epoetin zeta (biosimilar forms for epoetin alpha): Silapo (STADA Arzneimittel AG) [22] Retacrit (Hospira, Pfizer Europe MA EEIG) [23] Miscellaneous:
n/a n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a n/a Wikidata View/Edit Human Erythropoietin (/ ɪ ˌ r ɪ θ r oʊ ˈ p ɔɪ. ɪ t ɪ n, - r ə -, - p ɔɪ ˈ ɛ t ɪ n, - ˈ iː t ɪ n / ; EPO), also known as erythropoetin, haematopoietin, or haemopoietin, is a glycoprotein cytokine secreted mainly by the kidneys ...
According to Roche, the product has the longest half-life of all FDA-approved erythropoiesis-stimulating agents (ESAs): up to 6 times longer than darbepoetin alfa and up to 20 times longer than epoetin. CERAs thus promise both lower dosing—significant owing to the high inherent cost of manufacturing recombinant protein drugs—and less ...
The FDA determined that the data presented in a 2022 color additive petition show that this ingredient causes cancer in male laboratory rats exposed to high levels of FD&C Red No. 3 because of a ...
Luspatercept is indicated for the treatment of adults with transfusion-dependent anemia due to very low, low and intermediate-risk myelodysplastic syndromes (MDS) with ring sideroblasts, who had an unsatisfactory response to or are ineligible for erythropoietin-based therapy.
The schedule also gets lighter as it only faces one ranked opponent − Alabama − in the last five regular season contests. Nebraska. Current projected seed: No. 9 (Midwest)
epoetin alfa-epbx/Retacrit: epoetin alfa/Procrit June 2018 [152] [153] pegfilgrastim-jmdb/Fulphila: pegfilgrastim/Neulasta July 2018 [154] filgrastim-aafi/Nivestym: filgrastim/Neupogen October 2018 [155] adalimumab-adaz/Hyrimoz: adalimumab/Humira November 2018 [156] pegfilgrastim-cbqv/Udenyca: pegfilgrastim/Neulasta November 2018 [157 ...
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