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  2. Animal models of depression - Wikipedia

    en.wikipedia.org/wiki/Animal_models_of_depression

    It is difficult to develop an animal model that perfectly reproduces the symptoms of depression in patients. It is generic that 3 standards may be used to evaluate the reliability of an animal version of depression: the phenomenological or morphological appearances (face validity), a comparable etiology (assemble validity), and healing similarities (predictive validity).

  3. Sleep deprivation - Wikipedia

    en.wikipedia.org/wiki/Sleep_deprivation

    [citation needed] People who are sleep deprived in general also do not provide their bodies with sufficient time for an adequate immunological memory to form and, thus, can fail to benefit from vaccination. [85] People who sleep less than six hours a night are more susceptible to infection and are more likely to catch a cold or flu.

  4. Animal psychopathology - Wikipedia

    en.wikipedia.org/wiki/Animal_psychopathology

    Cortisol levels are elevated in half of people with major depression, it is the hippocampal region that is affected by both. Stress can have negative effects on gastrointestinal function causing ulcers, and it can also decrease sex drive, affect sleeping patterns and elevate blood pressure but it can also stimulate and motivate. When animals ...

  5. Sleep in animals - Wikipedia

    en.wikipedia.org/wiki/Sleep_in_animals

    Sleep can follow a physiological or behavioral definition. In the physiological sense, sleep is a state characterized by reversible unconsciousness, special brainwave patterns, sporadic eye movement, loss of muscle tone (possibly with some exceptions; see below regarding the sleep of birds and of aquatic mammals), and a compensatory increase following deprivation of the state, this last known ...

  6. Biology of depression - Wikipedia

    en.wikipedia.org/wiki/Biology_of_depression

    Sleep deprivation and light therapy both target the same brain neurotransmitter system and brain areas as antidepressant drugs, and are now used clinically to treat depression. [28] Light therapy, sleep deprivation and sleep time displacement (sleep phase advance therapy) are being used in combination quickly to interrupt a deep depression in ...

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  8. Psychological stress and sleep - Wikipedia

    en.wikipedia.org/wiki/Psychological_stress_and_Sleep

    Stress and sleep deprivation can negatively impact daily life. These factors often lead to decreased work performance, increased absenteeism, and a higher risk of illness. People who consistently lack sleep are more susceptible to heart disease, diabetes, and mental health issues such as depression and anxiety.

  9. Sleep disorder - Wikipedia

    en.wikipedia.org/wiki/Sleep_disorder

    One factor that could explain this change in sleep architecture is a disruption in the circadian rhythm, which regulates sleep. [19] This disruption can lead to sleep disturbances. [19] Some studies show that people with Alzheimer's disease have a delayed circadian rhythm, whereas in normal aging, an advanced circadian rhythm is present. [19] [20]

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    animal models of depressionidiopathic insomnia