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  2. Mitophagy - Wikipedia

    en.wikipedia.org/wiki/Mitophagy

    Mitophagy impaired due to the deletion of autophagy-related genes led to a loss of HSC function, more likely as a result of mitochondrial damage that stimulated excessive ROS production. On the contrary, mitophagy induction appeared to be protective for HSC and directed stem cell differentiation to the myeloid lineage. [22]

  3. Doctors Explain What Autophagy Is—And, How to Enhance it - AOL

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  4. Management of obesity - Wikipedia

    en.wikipedia.org/wiki/Management_of_obesity

    [84] [85] Preoperative weight loss can reduce operative time and hospital stay. [84] [86] [87] although there is insufficient evidence whether preoperative weight loss may be beneficial to reduce long-term morbidity or complications. [87] [88] Weight loss and decreases in liver size may be independent from the amount of calorie restriction. [85]

  5. Weight loss - Wikipedia

    en.wikipedia.org/wiki/Weight_loss

    Intentional weight loss is the loss of total body mass as a result of efforts to improve fitness and health, or to change appearance through slimming. Weight loss is the main treatment for obesity, [1] [2] [3] and there is substantial evidence this can prevent progression from prediabetes to type 2 diabetes with a 7–10% weight loss and manage cardiometabolic health for diabetic people with a ...

  6. Autophagy - Wikipedia

    en.wikipedia.org/wiki/Autophagy

    Defects in autophagy have been linked to various human diseases, including neurodegeneration and cancer, and interest in modulating autophagy as a potential treatment for these diseases has grown rapidly. [6] [7] Four forms of autophagy have been identified: macroautophagy, microautophagy, chaperone-mediated autophagy (CMA), and crinophagy.

  7. Autophagy protein 5 - Wikipedia

    en.wikipedia.org/wiki/Autophagy_protein_5

    Autophagy protein 5 (ATG5) is a protein that, in humans, is encoded by the ATG5 gene located on chromosome 6. It is an E3 ubi autophagic cell death . ATG5 is a key protein involved in the extension of the phagophoric membrane in autophagic vesicles.

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