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  2. Seizure threshold - Wikipedia

    en.wikipedia.org/wiki/Seizure_threshold

    The term seizure threshold is used to describe the balance between excitatory (glutaminergic) and inhibitory (GABA-ergic) forces in the brain which affect how susceptible a person is to seizures. Those diagnosed with epilepsy or certain other neurological conditions are more vulnerable to seizures if the threshold is reduced, and should be ...

  3. Methocarbamol - Wikipedia

    en.wikipedia.org/wiki/Methocarbamol

    Methocarbamol, sold under the brand name Robaxin among others, is a medication used for short-term musculoskeletal pain. [3] [4] It may be used together with rest, physical therapy, and pain medication. [3] [5] [6] It is less preferred in low back pain. [3] It has limited use for rheumatoid arthritis and cerebral palsy.

  4. Neuromuscular-blocking drug - Wikipedia

    en.wikipedia.org/wiki/Neuromuscular-blocking_drug

    Harmful metabolite called laudanosine (lowering seizure threshold); greater accumulation in individuals with renal failure; Cisatracurium (Nimbex) 90 60–80 does not cause release of histamine refrigerated Vecuronium (Norcuron) 60 30–40 [13] Few, [13] may cause prolonged paralysis [13] and promote muscarinic block widely [13] non-refrigerated

  5. Threshold potential - Wikipedia

    en.wikipedia.org/wiki/Threshold_potential

    In electrophysiology, the threshold potential is the critical level to which a membrane potential must be depolarized to initiate an action potential. In neuroscience, threshold potentials are necessary to regulate and propagate signaling in both the central nervous system (CNS) and the peripheral nervous system (PNS).

  6. Anticonvulsant - Wikipedia

    en.wikipedia.org/wiki/Anticonvulsant

    The Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) study showed that most blood concentrations in breastfed infants of mothers taking carbamazepine, oxcarbazepine, valproate, levetiracetam, and topiramate were quite low, especially in relationship to the mother's level and what the fetal level would have been ...

  7. Depressant - Wikipedia

    en.wikipedia.org/wiki/Depressant

    Methocarbamol is a popular drug that is commonly known as Robaxin and is over-the-counter in some countries. It is a carbamate with muscle relaxant effects. Tetrabamate is a controversial drug that is a combination of febarbamate, difebarbamate, and phenobarbital. It is marketed in Europe and has been largely, but not completely, discontinued.

  8. Methohexital - Wikipedia

    en.wikipedia.org/wiki/Methohexital

    It has been commonly used to induce deep sedation or general anesthesia for surgery and dental procedures. Unlike many other barbiturates, methohexital actually lowers the seizure threshold, a property that makes it particularly useful when anesthesia is provided for an electroconvulsive therapy (ECT). [4]

  9. Generalized tonic–clonic seizure - Wikipedia

    en.wikipedia.org/wiki/Generalized_tonic–clonic...

    A generalized tonic–clonic seizure, commonly known as a grand mal seizure or GTCS, [1] is a type of generalized seizure that produces bilateral, convulsive tonic and clonic muscle contractions. Tonic–clonic seizures are the seizure type most commonly associated with epilepsy and seizures in general and the most common seizure associated ...

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