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Cell mechanics is a sub-field of biophysics that focuses on the mechanical properties and behavior of living cells and how it relates to cell function. [1] It encompasses aspects of cell biophysics , biomechanics , soft matter physics and rheology , mechanobiology and cell biology .
By studying these mechanical properties, greater insight will be gained in regards to disease. Thus, the goal of understanding cell biomechanics is to combine theoretical, experimental, and computational approaches to construct a realistic description of cell mechanical behaviors to provide new insights on the role of mechanics in disease. [2]
Page of one of the first works of Biomechanics (De Motu Animalium of Giovanni Alfonso Borelli) in the 17th centuryBiomechanics is the study of the structure, function and motion of the mechanical aspects of biological systems, at any level from whole organisms to organs, cells and cell organelles, [1] using the methods of mechanics. [2]
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In 1903, Nikolai K. Koltsov proposed that the shape of cells was determined by a network of tubules that he termed the cytoskeleton. The concept of a protein mosaic that dynamically coordinated cytoplasmic biochemistry was proposed by Rudolph Peters in 1929 [12] while the term (cytosquelette, in French) was first introduced by French embryologist Paul Wintrebert in 1931.
Cell biophysics (or cellular biophysics) is a sub-field of biophysics that focuses on physical principles underlying cell function. Sub-areas of current interest include statistical models of intracellular signaling dynamics, intracellular transport, cell mechanics (including membrane and cytoskeletal mechanics), molecular motors, biological electricity and genetic network theory.
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The cell membrane: Amphiphile: Added reference, Diff: The cytoplasm and cell organelles: Cytoskeleton: image and description, diff: The nucleus and DNA replication-- Protein synthesis-- Cell growth and division: Cleavage furrow Cytokinesis: added short description, diff New section about clinical significance, diff: Cellular differentiation ...