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Vitamin D analogs may be useful with steroids; steroids alone have a higher rate of side effects. [82] Vitamin D analogs may allow lower doses of steroids to be used. [86] Another topical therapy used to treat psoriasis is a form of balneotherapy, which involves daily baths in saltwater, such as the Dead Sea, combined with sun exposure. This is ...
Vitamin D deficiency or hypovitaminosis D is a vitamin D level that is below normal. It most commonly occurs in people when they have inadequate exposure to sunlight, particularly sunlight with adequate ultraviolet B rays (UVB).
Calcipotriol, also known as calcipotriene, is a synthetic derivative of calcitriol, a form of vitamin D. It is used in the treatment of psoriasis. [1] It is safe for long-term application in psoriatic skin conditions. [medical citation needed] It was patented in 1985 and approved for medical use in 1991. [2]
Vitamin D deficiency in early life may contribute to biological processes that raise the risk of autoimmune conditions, including type 1 diabetes, a study in mice has shown.
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Holick made discoveries in the field of vitamin D that have led to novel therapies for metabolic bone diseases, hypocalcemic disorders, and psoriasis.He is author of more than 400 publications about the biochemistry, physiology, metabolism and photobiology of vitamin D and the pathophysiology of vitamin D deficiency.
Vitamin D is known as an immune regulator that assists in the adaptive and innate immune response. [86] [87] A deficiency in vitamin D, from hereditary or environmental influence, can lead to a more inefficient and weaker immune response and seen as a contributing factor to the development of autoimmune diseases. [87]
This condition can be caused by vitamin D, calcium or phosphorus deficiency. [86] Vitamin D deficiency remains the main cause of rickets among young infants in most countries because breast milk is low in vitamin D, and darker skin, social customs, and climatic conditions can contribute to inadequate sun exposure.
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