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Hydralazine is often used to treat hypertension in pregnancy, though, with either labetalol and/or methyldopa. [11] Hydralazine is commonly used in combination with isosorbide dinitrate for the treatment of congestive heart failure in black populations. This preparation, isosorbide dinitrate/hydralazine, was the first race-based prescription ...
While hydralazine is the most well-known compound in this class, other related drugs such as dihydralazine also belong to the hydrazinophthalazine family and exhibit similar antihypertensive properties. These compounds have been in clinical use since the mid-20th century, with hydralazine being discovered in the 1940s and approved by the FDA in ...
[42] [43] Hydralazine and its derivatives are also used in the treatment of severe hypertension, although they should be avoided in emergencies. [43] They are no longer indicated as first-line therapy for high blood pressure due to side effects and safety concerns, but hydralazine remains a drug of choice in gestational hypertension. [42]
The researchers called for interventions to help reduce heart disease risk factors. "Any medical or clinical therapies that can treat the risk factors that contribute to CVD are essential ...
The combination of isosorbide dinitrate/hydralazine is the only vasodilator regimen, other than ACE inhibitors or angiotensin II receptor antagonists, with proven survival benefits. This combination appears to be particularly beneficial in CHF patients with an African American background, who respond less effectively to ACEI therapy.
Cardiovascular disease, including stroke, remains the leading cause of death in the United States, according to the latest data from the American Heart Association (AHA). Lifestyle interventions ...
Options include sublingual or topical nitrates as well as oral hydralazine or clonidine. Ganglionic blockers can also be used to control sympathetic nervous system outflow. [29] [13] Epidural anesthesia has been demonstrated to be effective in reducing AD in women in labor. However, there is less evidence for its use in reducing AD during ...
Kittens knead their mother's mammary glands, or breasts, while nursing, likely to aid the release of milk. Animal experts call this process "milk let down," said Sung, who is based in Walnut Creek ...