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Bladder cancer is much more common in men than women; around 1.1% of men and 0.27% of women develop bladder cancer. [2] This makes bladder cancer the sixth most common cancer in men, and the seventeenth in women. [69] When women are diagnosed with bladder cancer, they tend to have more advanced disease and consequently a poorer prognosis. [69]
It accounts for 95% of bladder cancer cases and bladder cancer is in the top 10 most common malignancy disease in the world and is associated with approximately 200,000 deaths per year in the US. [ 2 ] [ 3 ] It is the second most common type of kidney cancer , but accounts for only five to 10 percent of all primary renal malignant tumors. [ 4 ]
Hereditary cancer syndromes underlie 5 to 10% of all cancers and there are over 50 identifiable hereditary forms of cancer. [5] Scientific understanding of cancer susceptibility syndromes is actively expanding: additional syndromes are being found, [6] the underlying biology is becoming clearer, and genetic testing is improving detection, treatment, and prevention of cancer syndromes. [7]
The bladder is an organ that stores urine until it is released from the body. Several conditions can affect the bladder including urinary tract infections, bladder stones, bladder cancer, overactive bladder, cystitis, interstitial cystitis, abscess, fistula, and urinary incontinence. [4] [5] [1]
Diagnosis is typically based on measuring the amount of urine in the bladder after urinating. [21] Treatment is typically with a catheter either through the urethra or lower abdomen. [22] Transitional cell carcinoma or bladder cancer is any of several types of cancer arising from the tissues of the urinary bladder. [23]
Hereditary cancers are primarily caused by an inherited genetic defect. A cancer syndrome or family cancer syndrome is a genetic disorder in which inherited genetic mutations in one or more genes predisposes the affected individuals to the development of cancers and may also cause the early onset of these cancers. Although cancer syndromes ...
FMTC = familial medullary thyroid cancer Micrograph of a medullary thyroid carcinoma, as may be seen in MEN 2A and MEN 2B. H&E stain. MEN 2B is sometimes known as MEN 3 and the designation varies by institution (c.f. www.ClinicalReview.com). Although a variety of additional eponyms have been proposed for MEN2B (e.g. Williams-Pollock syndrome ...
Ureter cancer rarely causes problems in the early stages, but as the cancer progresses, there are often side effects. [5] Symptoms of ureteral cancer may include "blood in the urine (); diminished urine stream and straining to void (caused by urethral stricture); frequent urination and increased nighttime urination (); hardening of tissue in the perineum, labia, or penis; itching; incontinence ...
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