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Pantoprazole, sold under the brand name Protonix, among others, is a medication used for the treatment of stomach ulcers, short-term treatment of erosive esophagitis due to gastroesophageal reflux disease (GERD), maintenance of healing of erosive esophagitis, and pathological hypersecretory conditions including Zollinger–Ellison syndrome.
The most common side effect seen is constipation (2–3%). Less commonly reported side effects (<0.5%) include flatulence, headache, hypophosphatemia, xerostomia (dry mouth), and bezoar formation. [24] [25] [26] Use of this drug is not recommended for people with chronic kidney failure, as it might cause aluminium accumulation and toxicity.
Acetaminophen (paracetamol, Tylenol) can cause liver damage in dogs. The toxic dose is 150 mg/kg. [174] Ibuprofen * can cause gastrointestinal irritation, stomach ulcers, and kidney damage in dogs. [175] Naproxen (Aleve)* has a long half-life in dogs and can cause gastrointestinal irritation, anemia, melena (digested blood in feces), and vomiting.
They do so by irreversibly inhibiting the stomach's H + /K + ATPase proton pump. [1] The body eventually synthesizes new proton pumps to replace the irreversibly inhibited ones, a process driven by normal cellular turnover, which gradually restores acid production.
Megaloblastic anaemia; Methaemoglobinaemia; Erythema multiforme; Low blood sugar; Hepatitis (liver swelling); Crystalluria (crystals in the urine); Urinary obstruction causing difficulty passing urine
This is achieved by formulating capsules using the multiple-unit pellet system. Although the (S)-(−)-isomer is more potent in humans, the (R)-(+)-isomer is more potent in testings of rats, while the enantiomers are equipotent in dogs. [14] Dexlansoprazole (brand names: Kapidex, Dexilant) The proton pump inhibitor dexlansoprazole
[2] [3] In severe cases of bowel obstruction or constipation (such as those related to clozapine treatment) fecal vomiting has been identified as a cause of death. [ 4 ] Fecal vomiting occurs when the bowel is obstructed for some reason, and intestinal contents cannot move normally.
Protonix (pantoprazole): a proton pump inhibitor for treating dyspepsia, duodenal ulcers and Oesophagitis; Relistor (methylnaltrexone): a newly approved drug for constipation induced by opioids (co-marketed with Progenics) Surmontil (trimipramine): a tetracyclic antidepressant and the only psychotropic drug that shows no effect on REM sleep.